{"id":"W1625894348","doi":"10.1523/jneurosci.22-07-02427.2002","title":"Alterations in Exocytosis Induced by Neuronal Ca<sup>2+</sup>Sensor-1 in Bovine Chromaffin Cells","year":2002,"lang":"en","type":"article","venue":"Journal of Neuroscience","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":53,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital","funders":"Medical Research Council; Medical Research Council Canada","keywords":"Exocytosis; Chromaffin cell; Cell biology; Endocytosis; Biology; Munc-18; Phosphatidylinositol; Endocytic cycle; Green fluorescent protein; Secretion; Depolarization; Synaptic vesicle; Signal transduction; Biophysics; Adrenal medulla; Vesicle; Cell; Biochemistry; Catecholamine; Membrane; Endocrinology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001584963,0.0002139896,0.0004191975,0.0001200831,0.0001160715,0.0004407653,0.00024728,0.0002956528,0.0005418112],"category_scores_gemma":[0.0001487307,0.00009788943,0.0002974453,0.0002155923,0.0001919872,0.0003497304,0.0001667935,0.0004086023,0.0002289876],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007375418,"about_ca_system_score_gemma":0.0001561937,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002027678,"about_ca_topic_score_gemma":0.001384662,"domain_scores_codex":[0.9997662,0.00002414842,0.00003077938,0.00005283038,0.00006165562,0.00006452241],"domain_scores_gemma":[0.9998829,0.00002910113,0.00002542415,0.0000187548,0.00001707501,0.00002678747],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008912792,0.000007746873,0.0001930316,0.00002506846,0.000003946176,0.00006440566,0.00001583568,0.00002390298,0.9992837,0.00003669503,0.00001206777,0.0002445164],"study_design_scores_gemma":[0.00001912826,0.0001819249,0.02283638,0.000005896065,0.00001824471,0.0002670543,0.00008882394,0.001300412,0.9738903,0.00004090777,0.001341834,0.00000906469],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.996463,0.001431623,0.0008976568,0.00008086319,0.00003471391,0.000009403586,0.0004862784,0.00003875029,0.0005577735],"genre_scores_gemma":[0.9977113,0.0005074888,0.0005827592,0.00004223552,0.000005883445,0.00001298476,0.0004780993,0.00001254559,0.000646641],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002027678,"threshold_uncertainty_score":0.005351305,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02007677220407939,"score_gpt":0.2319749595558586,"score_spread":0.2118981873517792,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}