{"id":"W1625894348","doi":"10.1523/jneurosci.22-07-02427.2002","title":"Alterations in Exocytosis Induced by Neuronal Ca<sup>2+</sup>Sensor-1 in Bovine Chromaffin Cells","year":2002,"lang":"en","type":"article","venue":"Journal of Neuroscience","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":53,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital","funders":"Medical Research Council; Medical Research Council Canada","keywords":"Exocytosis; Chromaffin cell; Cell biology; Endocytosis; Biology; Munc-18; Phosphatidylinositol; Endocytic cycle; Green fluorescent protein; Secretion; Depolarization; Synaptic vesicle; Signal transduction; Biophysics; Adrenal medulla; Vesicle; Cell; Biochemistry; Catecholamine; Membrane; Endocrinology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001704585,0.0001098553,0.0001421195,0.0001347941,0.00004495828,0.00003332259,0.0002263623,0.00007194754,0.00003002266],"category_scores_gemma":[0.00005840642,0.0001048875,0.00006995563,0.00026942,0.00005537247,0.00002246402,0.00002230319,0.0002149232,0.000003345006],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001907197,"about_ca_system_score_gemma":0.00003956877,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002176105,"about_ca_topic_score_gemma":0.00003387042,"domain_scores_codex":[0.9988928,0.00006669242,0.0003844014,0.0002200529,0.0002261308,0.000209853],"domain_scores_gemma":[0.9995997,0.00001046987,0.0001239007,0.0001343085,0.00004296233,0.00008865781],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003040064,0.0001435965,0.001327701,0.000003318217,8.078856e-7,0.0000476613,0.0001016923,0.002126297,0.9957951,0.000001359052,0.0002548716,0.0001672472],"study_design_scores_gemma":[0.002637208,0.002495284,0.0590649,0.00006669857,0.00001891296,0.0003206751,0.0001314463,0.04374487,0.857861,0.00001374651,0.03312064,0.0005245832],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9984841,0.0001577212,0.0005819777,0.0004500838,0.0001540404,0.00006791129,0.000009071477,0.000001847333,0.00009318448],"genre_scores_gemma":[0.9989413,0.0002671182,0.00006847899,0.00044187,0.00008385264,0.000001493875,0.00001466032,0.000009049259,0.0001721897],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.137934,"threshold_uncertainty_score":0.4277186,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02007677220407939,"score_gpt":0.2319749595558586,"score_spread":0.2118981873517792,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}