{"id":"W1629308315","doi":"10.4049/jimmunol.0801795","title":"<i>Histoplasma capsulatum</i> Cell Wall β-Glucan Induces Lipid Body Formation through CD18, TLR2, and Dectin-1 Receptors: Correlation with Leukotriene B4 Generation and Role in HIV-1 Infection","year":2009,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Fungal Infections and Studies","field":"Medicine","cited_by":68,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"Department of Science and Technology, Ministry of Science and Technology, India","keywords":"TLR2; Leukotriene B4; Biology; Receptor; Lipid signaling; Immunology; Leukotriene; Innate immune system; Microbiology; Inflammation; Immune system; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003588604,0.0001175466,0.0002455075,0.0001683478,0.0001975801,0.00001781607,0.00002761924,0.0001055596,0.000006584381],"category_scores_gemma":[0.00005923201,0.00007533514,0.00002513018,0.0001895336,0.00007781156,0.0004119597,0.0000131193,0.0003862254,0.00000201481],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001345643,"about_ca_system_score_gemma":0.00004450893,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000242462,"about_ca_topic_score_gemma":0.0001967758,"domain_scores_codex":[0.9991941,0.0001309913,0.000361316,0.00008258194,0.0001005102,0.0001305326],"domain_scores_gemma":[0.9993247,0.00007017831,0.00032521,0.0000878981,0.0001677521,0.00002426698],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.002379305,0.0005383885,0.05932109,0.00005032332,0.0001998192,0.00001478211,0.02124915,0.001751066,0.8932071,0.0005057693,0.001489163,0.01929404],"study_design_scores_gemma":[0.01007834,0.01427215,0.8082018,0.0003701208,0.0005933139,0.008159073,0.003661529,0.003657385,0.1417983,0.0007739441,0.00799799,0.0004359903],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9939952,0.00273315,0.001039412,0.001216729,0.0002723158,0.0001640349,4.691457e-7,0.00001097376,0.0005676684],"genre_scores_gemma":[0.9951862,0.004089796,0.0003018843,0.0001577765,0.0001494469,0.000002249548,0.000005210954,0.000006844667,0.0001006161],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7514088,"threshold_uncertainty_score":0.3072078,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01069510621101316,"score_gpt":0.2257408888967509,"score_spread":0.2150457826857377,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}