{"id":"W1629308315","doi":"10.4049/jimmunol.0801795","title":"<i>Histoplasma capsulatum</i> Cell Wall β-Glucan Induces Lipid Body Formation through CD18, TLR2, and Dectin-1 Receptors: Correlation with Leukotriene B4 Generation and Role in HIV-1 Infection","year":2009,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Fungal Infections and Studies","field":"Medicine","cited_by":68,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"Department of Science and Technology, Ministry of Science and Technology, India","keywords":"TLR2; Leukotriene B4; Biology; Receptor; Lipid signaling; Immunology; Leukotriene; Innate immune system; Microbiology; Inflammation; Immune system; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001085151,0.0003379261,0.0001506602,0.0001740297,0.00008014859,0.0001959787,0.00008671371,0.0002268607,0.0007793705],"category_scores_gemma":[0.00007959654,0.0001163199,0.0002083921,0.0001149912,0.0001371345,0.0001305284,0.0001375342,0.0003549184,0.0002784196],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001811136,"about_ca_system_score_gemma":0.00007490134,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002448152,"about_ca_topic_score_gemma":0.0002711585,"domain_scores_codex":[0.9998957,0.00002201121,0.00001025137,0.00001723415,0.00001359589,0.00004116474],"domain_scores_gemma":[0.9999084,0.0000108239,0.00003893184,0.000008150283,0.000009749636,0.00002379974],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002343864,0.00003947564,0.0005817399,0.00002965801,0.000003141022,0.00008105161,0.000007941199,0.00001094613,0.9984421,0.00001270019,0.00002550748,0.0005313437],"study_design_scores_gemma":[0.00003421783,0.0009438805,0.06043916,0.00001202486,0.0000184014,0.0006562392,0.00006736019,0.000433558,0.9364496,0.0000411708,0.0008995807,0.000004711474],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971536,0.001115173,0.000527662,0.00006598215,0.00001243688,0.00002665391,0.0002106419,0.00003956463,0.0008481622],"genre_scores_gemma":[0.9975764,0.0004769548,0.000561248,0.00008588228,0.00001308615,0.0000296793,0.0004634822,0.000006338564,0.0007868715],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007793705,"threshold_uncertainty_score":0.002607226,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01069510621101316,"score_gpt":0.2257408888967509,"score_spread":0.2150457826857377,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}