{"id":"W1633890482","doi":"10.1158/1538-7445.am2015-2488","title":"Abstract 2488: FGFR4 as a potential therapeutic target for monoclonal antibody based intervention in rhabdomyosarcoma","year":2015,"lang":"en","type":"article","venue":"Cancer Research","topic":"Fibroblast Growth Factor Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; BC Cancer Agency","funders":"","keywords":"Monoclonal antibody; Alveolar rhabdomyosarcoma; Cancer research; Antibody; Fibroblast growth factor receptor 4; Immunohistochemistry; Embryonal rhabdomyosarcoma; Immunogen; Biology; Cancer; Molecular biology; Medicine; Pathology; Immunology; Rhabdomyosarcoma; Sarcoma; Receptor; Internal medicine; Fibroblast growth factor; Fibroblast growth factor receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001883533,0.0002977642,0.00017847,0.0002076761,0.00008419508,0.0001439265,0.0002124121,0.0003372152,0.002655212],"category_scores_gemma":[0.0001024096,0.00007537554,0.0002488773,0.0001027704,0.0001051735,0.0001160408,0.0001191575,0.0003087178,0.0006794704],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002716323,"about_ca_system_score_gemma":0.0001688508,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003702863,"about_ca_topic_score_gemma":0.0004013628,"domain_scores_codex":[0.9999228,0.00001640718,0.000007864392,0.00001003841,0.0000207605,0.00002223953],"domain_scores_gemma":[0.999957,0.00000835831,0.000009972659,0.000003639287,0.00001289793,0.00000817432],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002385726,0.00008491321,0.000736293,0.0001474681,0.00001439847,0.0001951815,0.00001047054,0.0001686816,0.9905214,0.000147375,0.0003512176,0.007383997],"study_design_scores_gemma":[0.0001178956,0.00157467,0.009251697,0.00003285699,0.0001003508,0.00208496,0.0000174329,0.001096102,0.9693676,0.00009349568,0.01625675,0.000006226982],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9759383,0.009234398,0.006641155,0.0004185048,0.0001262006,0.0001656985,0.000672536,0.0002045698,0.00659879],"genre_scores_gemma":[0.9810479,0.003733202,0.007442798,0.0001514737,0.00005601304,0.00009397323,0.001342921,0.0000193617,0.006112264],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002655212,"threshold_uncertainty_score":0.008882582,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07861003281696348,"score_gpt":0.4443510188095365,"score_spread":0.365740985992573,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}