{"id":"W1636692034","doi":"10.1002/rmv.1853","title":"Protein/peptide‐based entry/fusion inhibitors as anti‐HIV therapies: challenges and future direction","year":2015,"lang":"en","type":"review","venue":"Reviews in Medical Virology","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"Canadian Institutes of Health Research","keywords":"Enfuvirtide; Human immunodeficiency virus (HIV); Peptide; Medicine; Drug; Computational biology; Clinical trial; Pharmacology; Biology; Virology; Gp41; Immunology; Biochemistry; Internal medicine; Epitope; Antigen","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002394408,0.00074166,0.001288724,0.001097817,0.0004229554,0.002311327,0.0008621114,0.001923179,0.004412457],"category_scores_gemma":[0.000960051,0.0003238397,0.0004634349,0.001091284,0.0012464,0.003550417,0.001058234,0.003334003,0.003238543],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008713022,"about_ca_system_score_gemma":0.00152028,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004708683,"about_ca_topic_score_gemma":0.001195524,"domain_scores_codex":[0.9994341,0.0001777787,0.00005247645,0.00007773473,0.0001824224,0.00007553726],"domain_scores_gemma":[0.9992261,0.000401541,0.00009611954,0.00002910949,0.0001648872,0.00008221384],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001510212,0.0001650372,0.0003277002,0.01016468,0.00004131793,0.0004904167,0.0002844216,0.0007577674,0.01501507,0.03274625,0.02716947,0.9126868],"study_design_scores_gemma":[0.00001886914,0.000276811,0.000313449,0.001789376,0.00004098062,0.001287532,0.0002143679,0.0003712603,0.004170841,0.00984434,0.9816446,0.00002745951],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0004790576,0.9934101,0.001104022,0.001968911,0.000393933,0.00001010428,0.00001301089,0.0000227416,0.002598202],"genre_scores_gemma":[0.002958339,0.9920923,0.001790185,0.0009101084,0.0004308297,0.00001958317,0.00002525311,0.000008946866,0.001764408],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004412457,"threshold_uncertainty_score":0.01476109,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04661965197020546,"score_gpt":0.3499346437298625,"score_spread":0.303314991759657,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}