{"id":"W1637744645","doi":"10.3233/jad-2011-110770","title":"Folate/vitamin-B12 Prevents Chronic Hyperhomocysteinemia-Induced Tau Hyperphosphorylation and Memory Deficits in Aged Rats","year":2011,"lang":"en","type":"article","venue":"Journal of Alzheimer s Disease","topic":"Folate and B Vitamins Research","field":"Medicine","cited_by":53,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"","keywords":"Hyperhomocysteinemia; Homocysteine; Vitamin B12; Endocrinology; Hyperphosphorylation; Internal medicine; Kinase; Medicine; Glycogen synthase; GSK-3; Hippocampus; Chemistry; Biochemistry; Glycogen","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001844148,0.0005395527,0.0006083733,0.0007433855,0.0002347487,0.0002052246,0.000333438,0.0005139445,0.0008714541],"category_scores_gemma":[0.0001826827,0.0002795508,0.0002505525,0.0001881853,0.0003593185,0.0002741022,0.0002417204,0.0006771678,0.0002138598],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003034449,"about_ca_system_score_gemma":0.000431904,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002880309,"about_ca_topic_score_gemma":0.004812579,"domain_scores_codex":[0.9998835,0.000015939,0.00001580483,0.00002353902,0.00001914173,0.00004191313],"domain_scores_gemma":[0.9997253,0.00001469266,0.0001074352,0.00002984934,0.00003486365,0.00008788868],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003241935,0.0005452619,0.000570746,0.0001042803,0.0000396774,0.0001131052,0.00006326557,0.00006849151,0.9892953,0.00007355057,0.00009319191,0.005791237],"study_design_scores_gemma":[0.0003761128,0.009434091,0.0112583,0.00004024465,0.0001649153,0.0003571058,0.0001255355,0.0007532694,0.9743756,0.0002154191,0.002878122,0.00002134719],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997237,0.001487398,0.0006675217,0.00007398617,0.00002174495,0.00001841872,0.0001136751,0.0001097993,0.0002704191],"genre_scores_gemma":[0.9935363,0.001579128,0.00178819,0.00006702666,0.00001906576,0.00005285071,0.0002734102,0.00002251559,0.002661523],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002880309,"threshold_uncertainty_score":0.005727112,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04785001731405438,"score_gpt":0.2940619147992876,"score_spread":0.2462118974852332,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}