{"id":"W1639287113","doi":"10.4049/jimmunol.174.12.8027","title":"Lack of Chemokine Receptor CCR5 Promotes Murine Fulminant Liver Failure by Preventing the Apoptosis of Activated CD1d-Restricted NKT Cells","year":2005,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":83,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Canadian Association of Gastroenterology; Health Canada; Fondation pour la Recherche Médicale; National Cancer Institute; National Institutes of Health; Canadian Institutes of Health Research; Canadian Liver Foundation","keywords":"CD1D; Chemokine; Chemokine receptor CCR5; Fulminant hepatic failure; Natural killer T cell; Fulminant; Apoptosis; Immunology; Biology; Chemokine receptor; Cancer research; Medicine; Internal medicine; Inflammation; Immune system; T cell; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002289514,0.0003319549,0.000210238,0.0002265909,0.0001279081,0.0002930346,0.0001818242,0.000213126,0.0008403386],"category_scores_gemma":[0.0002323678,0.0001434332,0.0001618042,0.0000555092,0.0002466422,0.0002222444,0.0001590006,0.0005351453,0.0002446313],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003258941,"about_ca_system_score_gemma":0.0001807096,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006033668,"about_ca_topic_score_gemma":0.0009143265,"domain_scores_codex":[0.999711,0.00008179097,0.00002895319,0.00002783068,0.00004640626,0.0001040465],"domain_scores_gemma":[0.9997328,0.00004289213,0.00008117249,0.00002963388,0.00001784826,0.00009563982],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003566536,0.00007734223,0.0006345935,0.0000361305,0.000006676438,0.0001415052,0.00001882746,0.0001197767,0.9971854,0.0001648106,0.00005728882,0.001200971],"study_design_scores_gemma":[0.000122971,0.00170039,0.01150762,0.00001899874,0.00003476818,0.001091994,0.0000607478,0.002182164,0.9813672,0.00008954241,0.001815767,0.000007851194],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9981642,0.0005923582,0.0006808118,0.00005499437,0.000011418,0.00001045398,0.00006446137,0.00002919957,0.0003920313],"genre_scores_gemma":[0.9987373,0.0001823861,0.0004226107,0.00002133092,0.000004558356,0.00000974354,0.00009478659,0.000004781034,0.0005225824],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008403386,"threshold_uncertainty_score":0.002811193,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01178580876771552,"score_gpt":0.228040076661873,"score_spread":0.2162542678941575,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}