{"id":"W1642721665","doi":"10.1007/978-0-387-73657-0_102","title":"Phe-Aib Hydroxyethylene Dipeptide Isostere Synthesis","year":2009,"lang":"en","type":"article","venue":"Advances in experimental medicine and biology","topic":"Chemical Synthesis and Analysis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Isostere; Dipeptide; Chemistry; Combinatorial chemistry; Stereochemistry; Biochemistry; Peptide","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002247763,0.0004446367,0.0002449364,0.0002889583,0.0002600949,0.000200434,0.0003343796,0.0003484796,0.00489834],"category_scores_gemma":[0.000163778,0.0001532871,0.000193342,0.0002081163,0.0001480673,0.0003485129,0.0003446923,0.0006664657,0.002587678],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003179098,"about_ca_system_score_gemma":0.0002793329,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003410994,"about_ca_topic_score_gemma":0.000319396,"domain_scores_codex":[0.9998673,0.00002033858,0.00001076962,0.00002445368,0.00002567445,0.00005148676],"domain_scores_gemma":[0.9999286,0.00001066377,0.00001290036,0.00001820241,0.00001172067,0.0000180026],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003409609,0.0001137657,0.0001415335,0.0002498976,0.0000190766,0.0005391807,0.00008928005,0.0008102111,0.9672664,0.004897068,0.0008750902,0.02465763],"study_design_scores_gemma":[0.00002818818,0.0003335233,0.0001967067,0.000008925223,0.00001074527,0.0002303673,0.00001603731,0.0003638304,0.9817135,0.0002652924,0.01682146,0.0000114129],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7852411,0.00679137,0.1155159,0.001018615,0.0007558101,0.0009295361,0.002587954,0.001064217,0.0860955],"genre_scores_gemma":[0.935402,0.003714285,0.02094936,0.0002058438,0.00004952829,0.0003152958,0.001118645,0.00009099522,0.03815413],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00489834,"threshold_uncertainty_score":0.01638657,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01369354361744506,"score_gpt":0.3251795836790854,"score_spread":0.3114860400616404,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}