{"id":"W1644093871","doi":"10.1046/j.1365-2133.2000.03287.x","title":"Characterization of an in vitro model of human melanoma invasion based on reconstructed human skin","year":2000,"lang":"en","type":"article","venue":"British Journal of Dermatology","topic":"melanin and skin pigmentation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":74,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Sciences Centre","funders":"","keywords":"Dermis; Keratinocyte; Melanocyte; Melanoma; Human skin; Basement membrane; In vitro; Cell culture; Biology; Epidermis (zoology); Pathology; Cell biology; Medicine; Anatomy; Cancer research; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001075402,0.00007223424,0.0002399578,0.0001121544,0.00003154565,0.000007161811,0.0001222712,0.0001374139,0.00006678262],"category_scores_gemma":[0.0000151585,0.00008707253,0.0000591127,0.00005603043,0.00005914007,0.00001190575,0.000008179038,0.00008816077,3.508715e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000008651617,"about_ca_system_score_gemma":0.00004779188,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000204683,"about_ca_topic_score_gemma":0.00003980585,"domain_scores_codex":[0.9989648,0.0001656356,0.0005552707,0.0001121049,0.000103372,0.0000988071],"domain_scores_gemma":[0.9994205,0.000006256932,0.0003410334,0.0001039833,0.00008739672,0.00004085777],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002262016,0.0001672076,0.001598272,0.00001911495,0.00001031467,0.00005111006,0.00003289127,0.0001658341,0.9891073,0.00001164749,0.00001954958,0.008590541],"study_design_scores_gemma":[0.00172762,0.0003079236,0.01145437,0.00008303543,0.00001003662,0.001425989,0.00001817509,0.001928893,0.9828581,0.000097039,0.00001275646,0.0000760884],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9992899,0.00002883501,0.000252699,0.00002575589,0.0000338645,0.0000710267,0.00002480325,0.000001468554,0.0002717044],"genre_scores_gemma":[0.9989018,0.00005727586,0.0006084294,0.00007233609,0.00002822193,0.000001608781,0.0003048189,0.000009822338,0.00001569661],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0098561,"threshold_uncertainty_score":0.3550715,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01066207628344214,"score_gpt":0.2421419773145074,"score_spread":0.2314799010310652,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}