{"id":"W1644526687","doi":"10.1186/ar1371","title":"Menopause and hormone replacement therapy: effects on the immune system, arthritis and bone","year":2004,"lang":"en","type":"article","venue":"Arthritis Research","topic":"Estrogen and related hormone effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Canadian Arthritis Network; School of Medicine, University of California, San Diego; Menzies Institute for Medical Research; National Cancer Institute; Arthritis Society; University of North Carolina at Chapel Hill; Genentech; National Institutes of Health; Biogen; Lupus Research Institute; Pfizer; Natural Sciences and Engineering Research Council of Canada; Dutch Arthritis Association; Oesterreichische Nationalbank; Deutsche Forschungsgemeinschaft; Nuffield Foundation; Physiotherapy Foundation of Canada; Canadian Institutes of Health Research; National Institute of Arthritis and Musculoskeletal and Skin Diseases; Lupus Research Alliance; Wellcome Trust; Newcastle University; National Institute of Allergy and Infectious Diseases; Howard Hughes Medical Institute; Austrian Science Fund; Arthritis Foundation","keywords":"Medicine; Estrogen; Hormone replacement therapy (female-to-male); Menopause; Internal medicine; Vitamin D and neurology; Osteoporosis; Rheumatoid arthritis; Endocrinology; Physiology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001178019,0.0003306284,0.0005141076,0.0008270729,0.0002769027,0.0009588278,0.0003261869,0.0006400674,0.009660468],"category_scores_gemma":[0.001176646,0.0001353704,0.0005338467,0.0008102735,0.0005473149,0.0003736918,0.0005326322,0.0005469241,0.0004758892],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004292091,"about_ca_system_score_gemma":0.0006994784,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002474405,"about_ca_topic_score_gemma":0.003422695,"domain_scores_codex":[0.9993774,0.0003426778,0.00004387535,0.00005268101,0.0001332202,0.00005019954],"domain_scores_gemma":[0.9989311,0.0006550127,0.0002514888,0.00002031515,0.00006272708,0.00007927616],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.001944137,0.0005134817,0.08932055,0.009684823,0.0007077247,0.001149275,0.0005143707,0.0005081082,0.001941183,0.005047663,0.02793417,0.8607345],"study_design_scores_gemma":[0.0003718708,0.003304132,0.7086689,0.006388481,0.0009589107,0.003972416,0.0004731195,0.0002728057,0.0004587689,0.005333362,0.2697498,0.00004744538],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.0151281,0.9738528,0.00009677809,0.005371151,0.0004773524,0.00003074327,0.0003147186,0.00001235123,0.004715938],"genre_scores_gemma":[0.2123796,0.7739345,0.0007743404,0.003771991,0.004390375,0.00009782625,0.0002639949,0.000007614289,0.004379707],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.009660468,"threshold_uncertainty_score":0.03231746,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01148683009135521,"score_gpt":0.2712453432193199,"score_spread":0.2597585131279647,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}