{"id":"W1644526687","doi":"10.1186/ar1371","title":"Menopause and hormone replacement therapy: effects on the immune system, arthritis and bone","year":2004,"lang":"en","type":"article","venue":"Arthritis Research","topic":"Estrogen and related hormone effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Canadian Arthritis Network; School of Medicine, University of California, San Diego; Menzies Institute for Medical Research; National Cancer Institute; Arthritis Society; University of North Carolina at Chapel Hill; Genentech; National Institutes of Health; Biogen; Lupus Research Institute; Pfizer; Natural Sciences and Engineering Research Council of Canada; Dutch Arthritis Association; Oesterreichische Nationalbank; Deutsche Forschungsgemeinschaft; Nuffield Foundation; Physiotherapy Foundation of Canada; Canadian Institutes of Health Research; National Institute of Arthritis and Musculoskeletal and Skin Diseases; Lupus Research Alliance; Wellcome Trust; Newcastle University; National Institute of Allergy and Infectious Diseases; Howard Hughes Medical Institute; Austrian Science Fund; Arthritis Foundation","keywords":"Medicine; Estrogen; Hormone replacement therapy (female-to-male); Menopause; Internal medicine; Vitamin D and neurology; Osteoporosis; Rheumatoid arthritis; Endocrinology; Physiology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001258656,0.0001778521,0.0001931092,0.00007669901,0.0004816189,0.0001039263,0.0001266478,0.0001717281,0.000003975811],"category_scores_gemma":[0.0001377072,0.0001274126,0.00004109557,0.0001452517,0.0003009707,0.000006496355,0.0001946083,0.0003709752,0.00003386806],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002841709,"about_ca_system_score_gemma":0.00005360715,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009982607,"about_ca_topic_score_gemma":0.00001521644,"domain_scores_codex":[0.9981437,0.0003657441,0.000214717,0.0004496537,0.0003593323,0.0004668872],"domain_scores_gemma":[0.9991406,0.0001202266,0.00004099781,0.0004674402,0.00008141927,0.000149316],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006146854,0.00009749308,0.00007729259,0.00003266612,0.0001107743,0.0001710849,0.0001602322,0.000003194048,0.914395,0.00504208,0.0007653552,0.07853014],"study_design_scores_gemma":[0.007317189,0.007963023,0.001426418,0.0005797743,0.000005458696,0.0005696365,0.0002994831,0.000008957081,0.9725279,0.0004282439,0.008594903,0.0002790735],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7919253,0.2053003,0.000009457227,0.001024411,0.00004866009,0.0006902093,0.00000547532,0.00001867303,0.0009774341],"genre_scores_gemma":[0.8957517,0.1036252,0.00004923072,0.00009181813,0.0001200636,0.0001616946,0.00001766482,0.00002894414,0.0001537187],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1038264,"threshold_uncertainty_score":0.5195736,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01148683009135521,"score_gpt":0.2712453432193199,"score_spread":0.2597585131279647,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}