{"id":"W1648713449","doi":"10.4049/jimmunol.170.7.3739","title":"A New Model of Sheep Ig Diversification: Shifting the Emphasis Toward Combinatorial Mechanisms and Away from Hypermutation","year":2003,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Glycosylation and Glycoproteins Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":47,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Somatic hypermutation; Repertoire; Biology; Genetics; Somatic cell; Germline; Antibody Repertoire; Gene; Evolutionary biology; Gene rearrangement; Antibody; B cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004751552,0.0005061361,0.0007833794,0.0006456397,0.0005721931,0.001558519,0.001229412,0.001581654,0.002943911],"category_scores_gemma":[0.0004065284,0.0003531873,0.000666805,0.0002849691,0.001955718,0.003465702,0.001054812,0.001482873,0.0009602174],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005844401,"about_ca_system_score_gemma":0.0005712079,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002799429,"about_ca_topic_score_gemma":0.0003115486,"domain_scores_codex":[0.999698,0.00008140673,0.00001341611,0.0000879516,0.00007376233,0.00004534806],"domain_scores_gemma":[0.9997812,0.00005179277,0.00002613408,0.00004482504,0.00002593559,0.00007006632],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.0004951378,0.0001888089,0.003615405,0.0004984238,0.00008574829,0.002981502,0.0009880903,0.01493877,0.2237828,0.701712,0.004057847,0.04665556],"study_design_scores_gemma":[0.0001963767,0.00135499,0.003367973,0.0001242396,0.00006381483,0.009854187,0.0005117155,0.1027173,0.01718061,0.8167867,0.04773848,0.0001035491],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":"theoretical_or_conceptual","genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.3497353,0.008458845,0.5438669,0.01862897,0.001012516,0.0001607136,0.000209024,0.001525487,0.07640223],"genre_scores_gemma":[0.8477429,0.004085206,0.1189775,0.00364301,0.000513335,0.0003043899,0.0001789947,0.0001380487,0.02441661],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.002943911,"threshold_uncertainty_score":0.009848356,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02229732839903897,"score_gpt":0.2549613561985548,"score_spread":0.2326640277995158,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}