{"id":"W1650650594","doi":"","title":"Chapter 99 – Insulin Receptor PTP: PTP1B","year":2010,"lang":"en","type":"book-chapter","venue":"","topic":"Protein Tyrosine Phosphatases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Insulin receptor; Insulin; Leptin; Biology; Signal transduction; Autophosphorylation; Phosphorylation; Cell biology; Endocrinology; Internal medicine; Medicine; Obesity; Insulin resistance; Protein kinase A","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004294238,0.0008005279,0.0004546471,0.001103082,0.000369487,0.001713906,0.0009196444,0.001665015,0.08156345],"category_scores_gemma":[0.0005302504,0.0003185111,0.0003418152,0.0009652265,0.0004013314,0.001678554,0.001164706,0.001642329,0.07714634],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000769588,"about_ca_system_score_gemma":0.000633804,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006071016,"about_ca_topic_score_gemma":0.0008138962,"domain_scores_codex":[0.9996125,0.00003579628,0.00002873817,0.00008995468,0.0001982334,0.00003473888],"domain_scores_gemma":[0.9997812,0.00004680783,0.00003083205,0.00002184696,0.00007151466,0.00004780314],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001051387,0.0001861679,0.0001706225,0.001374965,0.00001990345,0.0002332437,0.00008205495,0.000509113,0.01368347,0.01675866,0.5408849,0.4259918],"study_design_scores_gemma":[0.0000050743,0.00003411632,0.0002273893,0.000218069,0.000003721154,0.0002463096,0.000008587084,0.0000731076,0.0009531688,0.001872196,0.9963536,0.000004722282],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"other","genre_gemma":"other","genre_scores_codex":[0.003354147,0.3471408,0.01411079,0.01353139,0.05106913,0.0004635943,0.00157413,0.0008395237,0.5679165],"genre_scores_gemma":[0.01193415,0.2173033,0.004803677,0.003379322,0.02203957,0.0002496956,0.002072506,0.0002797659,0.737938],"genre_candidate":"other","genre_consensus":"other","teacher_disagreement_score":0.08156345,"threshold_uncertainty_score":0.2728569,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009849217933697273,"score_gpt":0.2193968670640949,"score_spread":0.2095476491303976,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}