{"id":"W1657991880","doi":"10.1371/journal.pone.0132794","title":"Evaluation of Live Recombinant Nonpathogenic Leishmania tarentolae Expressing Cysteine Proteinase and A2 Genes as a Candidate Vaccine against Experimental Canine Visceral Leishmaniasis","year":2015,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Research on Leishmaniasis Studies","field":"Medicine","cited_by":35,"is_retracted":true,"has_abstract":true,"ca_institutions":"Université Laval","funders":"Pasteur Institute of Iran; Tehran University of Medical Sciences and Health Services","keywords":"Leishmania infantum; Visceral leishmaniasis; Canine leishmaniasis; Virology; Immunogenicity; Immunology; Leishmaniasis; Antigen; Biology; Leishmania donovani; Recombinant DNA; Leishmania; Medicine; Parasite hosting; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":{"nature":"Retraction","reason":"Concerns/Issues about Data;Concerns/Issues about Results and/or Conclusions;Ethical Violations by Author;","date":"7/5/2019 0:00","openalex_flagged":true},"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002691705,0.0004070947,0.0004463313,0.0002056157,0.00009693083,0.0002705124,0.0002565425,0.0004123393,0.000529663],"category_scores_gemma":[0.0001771274,0.0001230954,0.00023552,0.000123925,0.000197893,0.0002594257,0.0001169413,0.0005835969,0.0001080084],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000188475,"about_ca_system_score_gemma":0.0001554049,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003232713,"about_ca_topic_score_gemma":0.0003932021,"domain_scores_codex":[0.9998255,0.0000389665,0.00001591005,0.00003862442,0.00003850599,0.00004251061],"domain_scores_gemma":[0.9998927,0.00002446032,0.00003083537,0.00001035404,0.00001559072,0.00002601683],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006444636,0.0005178909,0.0002971545,0.00009924907,0.00001514834,0.00003986544,0.00002531907,0.0001751993,0.9968117,0.00004860017,0.00002378579,0.001301738],"study_design_scores_gemma":[0.0003423908,0.04197305,0.006936602,0.00002519991,0.0001485292,0.0004816827,0.00007844829,0.001754819,0.9452912,0.00006468507,0.002889829,0.00001359174],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9987255,0.0004479318,0.0005185755,0.00003166552,0.00001868141,0.00003563062,0.00006599219,0.00001180667,0.0001442051],"genre_scores_gemma":[0.9971907,0.0005297465,0.001333744,0.00004327021,0.00001402164,0.00004155228,0.0002974484,0.000005948528,0.0005436057],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000529663,"threshold_uncertainty_score":0.001771927,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1018067644798377,"score_gpt":0.3239735108471089,"score_spread":0.2221667463672712,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}