{"id":"W1660334864","doi":"10.1016/j.bbrc.2015.10.025","title":"The P2X7/P2X4 interaction shapes the purinergic response in murine macrophages","year":2015,"lang":"en","type":"article","venue":"Biochemical and Biophysical Research Communications","topic":"Adenosine and Purinergic Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":65,"is_retracted":false,"has_abstract":false,"ca_institutions":"Centre hospitalier de l'Université Laval; Centre hospitalier universitaire de Québec","funders":"Canadian Institutes of Health Research","keywords":"Purinergic receptor; Receptor; Cell biology; Immunoprecipitation; Förster resonance energy transfer; Chemistry; Programmed cell death; Biophysics; Biology; Biochemistry; Fluorescence; Apoptosis; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002531561,0.0002399617,0.0002948002,0.000270929,0.0002879902,0.0005868028,0.0002230681,0.0006519734,0.001672986],"category_scores_gemma":[0.0001582955,0.0002266015,0.0002447863,0.0001631771,0.00036641,0.0003489171,0.0003106863,0.0009045493,0.0006084124],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00031062,"about_ca_system_score_gemma":0.000202697,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002428681,"about_ca_topic_score_gemma":0.000401999,"domain_scores_codex":[0.9996172,0.00008745313,0.00001980411,0.00004403286,0.0001040881,0.0001274889],"domain_scores_gemma":[0.999855,0.00003197813,0.0000278387,0.00001458753,0.00001928191,0.00005119959],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001843971,0.00001261724,0.0001661546,0.00001273584,0.000003226063,0.00007087478,0.00001630381,0.00007373698,0.9988477,0.0001923158,0.00003026157,0.0003896108],"study_design_scores_gemma":[0.0000375278,0.0002505346,0.007251066,0.000009881731,0.00001817019,0.0001864791,0.0002321722,0.00217774,0.9882775,0.0003612211,0.001189576,0.00000813322],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970657,0.0004635483,0.0008995452,0.0001830709,0.00002519131,0.000008907485,0.00009057803,0.00001311988,0.001250265],"genre_scores_gemma":[0.9965989,0.0003370029,0.0007739544,0.00009688418,0.00002506829,0.00002635212,0.0001148419,0.00001592916,0.002011113],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001672986,"threshold_uncertainty_score":0.005596697,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09687518673998448,"score_gpt":0.3989084211870647,"score_spread":0.3020332344470802,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}