{"id":"W1661694562","doi":"10.1007/s11739-015-1248-y","title":"Early goal-directed therapy vs usual care in the treatment of severe sepsis and septic shock: a systematic review and meta-analysis","year":2015,"lang":"en","type":"review","venue":"Internal and Emergency Medicine","topic":"Sepsis Diagnosis and Treatment","field":"Medicine","cited_by":31,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Medicine; Early goal-directed therapy; Septic shock; Sepsis; Randomized controlled trial; Meta-analysis; Observational study; Intensive care medicine; MEDLINE; Relative risk; Internal medicine; Emergency medicine; Severe sepsis; Confidence interval","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005005268,0.0006551245,0.00862381,0.0003560387,0.00003750963,0.000007737684,0.0001343126,0.0001428258,0.0007058032],"category_scores_gemma":[0.00008951282,0.0002597092,0.001113751,0.0006691437,0.0001041206,0.00003497886,0.00002748469,0.0001619495,0.000003452809],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001064266,"about_ca_system_score_gemma":0.0000518975,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001495934,"about_ca_topic_score_gemma":0.0002671604,"domain_scores_codex":[0.9967094,0.0005031462,0.001550891,0.000526973,0.0004859308,0.0002236256],"domain_scores_gemma":[0.9982256,0.000264205,0.0005763205,0.000521134,0.0002130804,0.0001996109],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"systematic_review","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.00008853326,0.0007972647,0.003173355,0.6717111,0.2839322,0.0001683736,0.00918394,9.262517e-8,1.359982e-7,0.000009478221,0.001696965,0.0292385],"study_design_scores_gemma":[0.001324795,0.003851051,0.0009797416,0.04811303,0.9033721,0.0002004019,0.0005098569,0.000002799093,1.832679e-7,0.0000079885,0.04139099,0.0002470563],"study_design_candidate":"meta_analysis","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.002494086,0.9933271,3.610694e-7,0.0005784521,0.00007558354,0.003164439,0.00008802206,0.00001501088,0.0002569188],"genre_scores_gemma":[0.002210665,0.9956364,0.0000112741,0.0001771489,0.00006807077,0.0008989627,0.0001046524,0.00002979497,0.0008630222],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.6235981,"threshold_uncertainty_score":0.9999855,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2149287652049836,"score_gpt":0.435997714282344,"score_spread":0.2210689490773604,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}