{"id":"W1664114449","doi":"10.4049/jimmunol.178.12.7859","title":"Follicular Dendritic Cell Secreted Protein (FDC-SP) Regulates Germinal Center and Antibody Responses","year":2007,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":34,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"University of Manitoba","keywords":"Germinal center; Follicular dendritic cells; B cell; Biology; Immunoglobulin class switching; Chemokine; CXCL13; CD40; Transgene; Chemotaxis; Dendritic cell; Antibody; Genetically modified mouse; T cell; Cell biology; Immune system; Immunology; Molecular biology; In vitro; Antigen-presenting cell; Receptor; Chemokine receptor; Cytotoxic T cell; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001526711,0.0002922074,0.0001677719,0.0002201601,0.0001876031,0.0002732969,0.0001225432,0.0003203826,0.0007612573],"category_scores_gemma":[0.0001686783,0.0000910219,0.0002328344,0.0001041225,0.0002055369,0.0001355858,0.0001763669,0.0004238221,0.0002555733],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000391504,"about_ca_system_score_gemma":0.0002576284,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007470545,"about_ca_topic_score_gemma":0.0006615521,"domain_scores_codex":[0.9998575,0.00002006871,0.00001015451,0.00003504498,0.00003089059,0.00004629468],"domain_scores_gemma":[0.999872,0.00001498687,0.00002396545,0.000008941359,0.00002551625,0.00005462614],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001225306,0.00002575913,0.001746267,0.00003907864,0.000005091557,0.0002171058,0.00002283567,0.00003993576,0.9954162,0.00006137003,0.0001145155,0.0021893],"study_design_scores_gemma":[0.00009960956,0.0008564555,0.09387705,0.00002258241,0.00007045649,0.003093689,0.0002247592,0.002099739,0.8865664,0.0002138458,0.01285729,0.00001809286],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9955018,0.002011435,0.001139739,0.00009765076,0.00003510445,0.00002994567,0.0002796852,0.00005692258,0.0008476992],"genre_scores_gemma":[0.9977255,0.000477004,0.0007301537,0.00005276474,0.00001286474,0.00001493072,0.0002965286,0.000008553678,0.0006816492],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007612573,"threshold_uncertainty_score":0.002840519,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007775305299863124,"score_gpt":0.2498581653886562,"score_spread":0.2420828600887931,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}