{"id":"W1664114449","doi":"10.4049/jimmunol.178.12.7859","title":"Follicular Dendritic Cell Secreted Protein (FDC-SP) Regulates Germinal Center and Antibody Responses","year":2007,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":34,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"University of Manitoba","keywords":"Germinal center; Follicular dendritic cells; B cell; Biology; Immunoglobulin class switching; Chemokine; CXCL13; CD40; Transgene; Chemotaxis; Dendritic cell; Antibody; Genetically modified mouse; T cell; Cell biology; Immune system; Immunology; Molecular biology; In vitro; Antigen-presenting cell; Receptor; Chemokine receptor; Cytotoxic T cell; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002633538,0.0003029487,0.000556787,0.0003949765,0.0004164474,0.00002620823,0.0005786656,0.000382877,0.0002742115],"category_scores_gemma":[0.0002544582,0.0001998294,0.0001956606,0.0002106803,0.0009448464,0.0001961556,0.0001391917,0.0009134291,0.00007425353],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005342629,"about_ca_system_score_gemma":0.0001192562,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004018288,"about_ca_topic_score_gemma":0.000003912538,"domain_scores_codex":[0.9967304,0.001442297,0.0009071595,0.0001746207,0.00008261265,0.0006628501],"domain_scores_gemma":[0.9976852,0.0009605059,0.0006470722,0.0004342107,0.0002438972,0.00002912904],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.01306312,0.0001750175,0.0006799994,0.00001717418,0.0005241848,0.0001010021,0.001081356,5.857285e-7,0.9807857,0.0001561757,0.0001517576,0.003263908],"study_design_scores_gemma":[0.004283154,0.001888955,0.03154515,0.0001572543,0.0001347005,0.01124935,0.001435593,7.348501e-7,0.9086358,0.0002077853,0.04020428,0.0002572649],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9248393,0.07304067,0.0004379005,0.0005298911,0.0006593205,0.0002671228,0.000007103245,0.00002490956,0.0001938397],"genre_scores_gemma":[0.9943321,0.002011457,0.0001421544,0.0001964524,0.00005398442,0.000002444879,0.00000955593,0.00003427531,0.00321761],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07214994,"threshold_uncertainty_score":0.8148808,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007775305299863124,"score_gpt":0.2498581653886562,"score_spread":0.2420828600887931,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}