{"id":"W1666594451","doi":"10.1002/14651858.cd003459.pub4","title":"Methotrexate for induction of remission in refractory Crohn's disease","year":2014,"lang":"en","type":"review","venue":"Cochrane Database of Systematic Reviews","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":269,"is_retracted":false,"has_abstract":true,"ca_institutions":"Robarts Clinical Trials","funders":"","keywords":"Medicine; Azathioprine; Adverse effect; Crohn's disease; Internal medicine; Methotrexate; Placebo; Refractory (planetary science); Randomized controlled trial; Relative risk; Thiopurine methyltransferase; Disease; Confidence interval; Alternative medicine; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00491993,0.0005650755,0.004367832,0.0002456605,0.00003116529,0.00001062186,0.0005993027,0.0002975526,0.00002455826],"category_scores_gemma":[0.007614783,0.0004071264,0.001163736,0.0001958393,0.00008869445,0.00001306312,0.0001589966,0.0001607361,0.00002017257],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004999621,"about_ca_system_score_gemma":0.0003745049,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004054334,"about_ca_topic_score_gemma":0.000004239037,"domain_scores_codex":[0.9929819,0.002247832,0.003540491,0.0006643184,0.0003097834,0.0002556893],"domain_scores_gemma":[0.9932533,0.0002477216,0.003720037,0.002334547,0.000237256,0.0002071541],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"systematic_review","study_design_gemma":"systematic_review","study_design_scores_codex":[0.00007683849,0.0000943604,0.000001722531,0.9819626,0.00007874597,0.00002131388,0.000008517465,6.713854e-7,0.0003109544,0.00003875567,0.001475543,0.01592995],"study_design_scores_gemma":[0.0003363187,0.00003887842,0.0000125002,0.6974733,0.001602162,0.000008427969,0.000006845768,0.00000923579,0.00003195968,0.000006198956,0.3001417,0.0003324126],"study_design_candidate":"systematic_review","study_design_consensus":"systematic_review","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00006592469,0.9894171,0.0009817501,0.000001840491,0.0002998644,0.008486451,0.0006899956,0.000005840042,0.00005123161],"genre_scores_gemma":[0.00001950897,0.9926148,0.001142386,0.00001127763,0.0001860836,0.001886871,0.003866174,0.00007526758,0.0001976471],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.2986662,"threshold_uncertainty_score":0.9998381,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07736138028848356,"score_gpt":0.384193988621814,"score_spread":0.3068326083333305,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}