{"id":"W1669284093","doi":"10.4049/jimmunol.0803977","title":"<i>P2Y</i> <i>2</i> Receptor Transcription Is Increased by NF-κB and Stimulates Cyclooxygenase-2 Expression and PGE2 Released by Intestinal Epithelial Cells","year":2009,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Adenosine and Purinergic Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":62,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval; Canadian Institutes of Health Research; Centre hospitalier universitaire de Québec; Université de Sherbrooke","funders":"National Institute on Aging; National Institute of Dental and Craniofacial Research; Canadian Institutes of Health Research","keywords":"Inflammatory bowel disease; Proinflammatory cytokine; Histone H4; Molecular biology; Transcription factor; Histone H3; Biology; Transcription (linguistics); Cell biology; Gene expression; Cancer research; Inflammation; Immunology; Gene; Internal medicine; Medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003039049,0.0001676732,0.0002126446,0.00003625877,0.0001175149,0.0000180519,0.0001756431,0.0001549752,0.00003034318],"category_scores_gemma":[0.0000473731,0.0001160458,0.00005640709,0.00004781103,0.000138938,0.00001295795,0.0000314787,0.0002385089,0.000001695678],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000007431063,"about_ca_system_score_gemma":0.00003212234,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003643861,"about_ca_topic_score_gemma":3.015038e-7,"domain_scores_codex":[0.9990171,0.0002094174,0.0003351931,0.0001475832,0.00009826238,0.000192481],"domain_scores_gemma":[0.9993848,0.00006135771,0.0002479727,0.0001451996,0.0000891551,0.00007149379],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001188794,0.00006439138,0.00006185475,0.000004733276,0.00004411932,0.000002471254,0.0001253098,0.000006315465,0.944892,0.000001967849,0.05227201,0.001336036],"study_design_scores_gemma":[0.001608061,0.001388838,0.0001176516,0.00004257892,0.00006003055,0.0002517702,0.0001143524,0.00002014614,0.9778572,0.0001047822,0.01830031,0.0001343095],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9647403,0.03247531,0.001651923,0.000896889,0.00008960304,0.00007898954,0.00003423767,0.000005246869,0.00002752534],"genre_scores_gemma":[0.9922063,0.006023051,0.000371471,0.001082128,0.0001523476,8.439648e-7,0.00002912423,0.0000132667,0.000121408],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0339717,"threshold_uncertainty_score":0.473221,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004338563825250187,"score_gpt":0.2045232472832351,"score_spread":0.200184683457985,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}