{"id":"W1669909471","doi":"10.1002/cncr.28256","title":"Impact of hemochromatosis gene mutations on cardiac status in doxorubicin‐treated survivors of childhood high‐risk leukemia","year":2013,"lang":"en","type":"article","venue":"Cancer","topic":"Chemotherapy-induced cardiotoxicity and mitigation","field":"Medicine","cited_by":160,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier Universitaire Sainte-Justine; McMaster University","funders":"National Heart, Lung, and Blood Institute; National Cancer Institute; National Institutes of Health; Children's Cardiomyopathy Foundation; Armstrong Foundation; Eunice Kennedy Shriver National Institute of Child Health and Human Development; University of Miami; National Institute of Allergy and Infectious Diseases; Lance Armstrong Foundation","keywords":"Medicine; Internal medicine; Cardiomyopathy; Cardiology; Hemochromatosis; Gastroenterology; Hereditary hemochromatosis; Cardiotoxicity; Heart failure; Myeloid leukemia; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008264055,0.0001508891,0.0004844013,0.0001754368,0.00002426004,0.000005054402,0.0000440838,0.0001198293,0.0002877631],"category_scores_gemma":[0.00004986533,0.0001268617,0.0002246448,0.0004109929,0.00008276812,0.0000744274,0.000008575344,0.0001572591,0.000009054716],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006734536,"about_ca_system_score_gemma":0.0003800328,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0479444,"about_ca_topic_score_gemma":0.0002037584,"domain_scores_codex":[0.9989992,0.00006202983,0.0003054048,0.0001960762,0.0002103203,0.0002269497],"domain_scores_gemma":[0.9992049,0.00007328393,0.0001732374,0.0002778877,0.0001604667,0.0001101674],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00006990491,0.0001262422,0.3365101,0.00004647212,0.0003919142,0.000001410281,0.001117551,0.001393089,0.6492,0.00001311893,0.0002573387,0.01087282],"study_design_scores_gemma":[0.001065126,0.0001622937,0.5277474,0.00009579266,0.00006370488,8.48955e-7,0.00007035506,0.00003679901,0.470654,0.00003718269,0.000005642187,0.00006082021],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9981172,0.0003510528,0.00001172984,0.00004586299,0.00009578561,0.0006101109,0.0002479869,0.00002467968,0.0004956053],"genre_scores_gemma":[0.9986795,0.0008362854,0.00009408646,0.00004557658,0.00007665953,0.00008004077,0.0001070207,0.00002704717,0.00005385314],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1912373,"threshold_uncertainty_score":0.9583954,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007840768675946715,"score_gpt":0.2664597627278731,"score_spread":0.2586189940519263,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}