{"id":"W1669909471","doi":"10.1002/cncr.28256","title":"Impact of hemochromatosis gene mutations on cardiac status in doxorubicin‐treated survivors of childhood high‐risk leukemia","year":2013,"lang":"en","type":"article","venue":"Cancer","topic":"Chemotherapy-induced cardiotoxicity and mitigation","field":"Medicine","cited_by":160,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier Universitaire Sainte-Justine; McMaster University","funders":"National Heart, Lung, and Blood Institute; National Cancer Institute; National Institutes of Health; Children's Cardiomyopathy Foundation; Armstrong Foundation; Eunice Kennedy Shriver National Institute of Child Health and Human Development; University of Miami; National Institute of Allergy and Infectious Diseases; Lance Armstrong Foundation","keywords":"Medicine; Internal medicine; Cardiomyopathy; Cardiology; Hemochromatosis; Gastroenterology; Hereditary hemochromatosis; Cardiotoxicity; Heart failure; Myeloid leukemia; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002748341,0.0001290098,0.0001478798,0.0002728202,0.000256225,0.0002687999,0.0001201744,0.0002310518,0.0006418386],"category_scores_gemma":[0.001669442,0.0000776166,0.000165378,0.0002912509,0.0002074576,0.0001804625,0.0001697937,0.0002755341,0.0000677415],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003915066,"about_ca_system_score_gemma":0.0002015653,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002281234,"about_ca_topic_score_gemma":0.00314696,"domain_scores_codex":[0.9998183,0.0000656921,0.00001394502,0.00002973295,0.00003214779,0.00004019033],"domain_scores_gemma":[0.9988037,0.0003041362,0.0005434419,0.00003782991,0.0000685053,0.0002423703],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0003047553,0.00002779902,0.9962605,0.000004187214,0.00001866493,0.0002608904,0.00006823755,0.00006677894,0.0005130468,0.000009249906,0.00004260641,0.002423214],"study_design_scores_gemma":[0.000008805315,0.0002217619,0.9983961,0.00000440315,0.0000220179,0.0009274678,0.0000753429,0.0001007502,0.0001506653,0.00001343585,0.00007699262,0.000002169551],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9997734,0.00009787916,0.000008847719,0.00001544909,0.000001048472,8.676005e-7,0.00001973545,7.629469e-7,0.00008183945],"genre_scores_gemma":[0.9999171,0.00002482128,0.00000815666,0.000005329908,0.000001553087,6.027392e-7,0.00002635786,2.86634e-7,0.00001567598],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002281234,"threshold_uncertainty_score":0.004535913,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007840768675946715,"score_gpt":0.2664597627278731,"score_spread":0.2586189940519263,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}