{"id":"W167817790","doi":"10.1016/s0079-6123(09)17906-2","title":"NR1 knockdown mice as a representative model of the glutamate hypothesis of schizophrenia","year":2009,"lang":"en","type":"review","venue":"Progress in brain research","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":53,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"National Institute on Drug Abuse; National Alliance for Research on Schizophrenia and Depression","keywords":"NMDA receptor; Neuroscience; Schizophrenia (object-oriented programming); Phencyclidine; Receptor; Gene knockdown; Glutamate receptor; Phenotype; Biology; Pharmacology; Psychology; Genetics; Psychiatry; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005662426,0.00116662,0.001518295,0.001055544,0.0001737022,0.0005353861,0.001119901,0.0009292561,0.001225754],"category_scores_gemma":[0.000287278,0.0002386611,0.0003018288,0.0008520809,0.0005753345,0.0006395704,0.0003976333,0.001626771,0.0009459421],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006516811,"about_ca_system_score_gemma":0.0006681166,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001026269,"about_ca_topic_score_gemma":0.002892128,"domain_scores_codex":[0.9999069,0.00001385653,0.00001555073,0.00002028673,0.00003356738,0.000009842257],"domain_scores_gemma":[0.9998455,0.00005806645,0.00002689372,0.00000789661,0.00004079014,0.00002085557],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003240709,0.000123268,0.0002995135,0.008932181,0.0001188513,0.001024703,0.00004007736,0.0006639143,0.03697556,0.01104227,0.04054971,0.8999058],"study_design_scores_gemma":[0.0001224437,0.0002297133,0.001988009,0.002121537,0.0003389191,0.00467461,0.00006746,0.0003718807,0.01007707,0.009097886,0.9708417,0.0000687681],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0007787255,0.9955285,0.001216683,0.000650611,0.0003637194,0.000009642096,0.00006333995,0.00003112344,0.001357667],"genre_scores_gemma":[0.0023667,0.9947811,0.001169568,0.0003154853,0.0001551167,0.00001465758,0.00009023096,0.000004923844,0.001102135],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001518295,"threshold_uncertainty_score":0.004728317,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1173030639537083,"score_gpt":0.4265851195371974,"score_spread":0.3092820555834891,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}