{"id":"W1679212756","doi":"10.3390/md13084784","title":"Fucoxanthin and Its Metabolite Fucoxanthinol in Cancer Prevention and Treatment","year":2015,"lang":"en","type":"review","venue":"Marine Drugs","topic":"Seaweed-derived Bioactive Compounds","field":"Agricultural and Biological Sciences","cited_by":136,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Moncton","funders":"Fondation de la recherche en santé du Nouveau-Brunswick","keywords":"Fucoxanthin; Angiogenesis; Cell cycle checkpoint; Apoptosis; Cancer; Biology; Cancer cell; Protein kinase B; Cancer research; PI3K/AKT/mTOR pathway; Metastasis; MAPK/ERK pathway; Biochemistry; Cell cycle; Pharmacology; Carotenoid; Signal transduction","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000258578,0.0005692985,0.0006835111,0.001887193,0.0002121229,0.0005160855,0.0004273374,0.0006794125,0.003681665],"category_scores_gemma":[0.0003308541,0.0001406452,0.0004014739,0.001125304,0.0002177299,0.0005463863,0.0004366504,0.001110539,0.001150656],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003372102,"about_ca_system_score_gemma":0.0005430461,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007386629,"about_ca_topic_score_gemma":0.001616806,"domain_scores_codex":[0.9998955,0.00001870709,0.00001715419,0.00001766503,0.00003901601,0.00001207411],"domain_scores_gemma":[0.9999024,0.00003850953,0.00001762391,0.000003256208,0.00002576517,0.00001247642],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008540284,0.0001030369,0.0001835632,0.01784542,0.00009574055,0.0002246791,0.00006582204,0.000321495,0.003606876,0.002053879,0.01409808,0.9613161],"study_design_scores_gemma":[0.00002228217,0.0001560861,0.001416008,0.003450525,0.0001289117,0.001804695,0.00006424213,0.0001081965,0.001217137,0.001449311,0.9901665,0.0000161643],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002263817,0.9986254,0.00008846738,0.0001451808,0.00009764889,0.000003895052,0.00001383059,0.000006189365,0.0007928917],"genre_scores_gemma":[0.001628117,0.99729,0.0001725071,0.00009883499,0.00008981718,0.000005697262,0.00002981203,0.000001240279,0.0006839627],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003681665,"threshold_uncertainty_score":0.01231641,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09257111651634521,"score_gpt":0.3418298982559392,"score_spread":0.249258781739594,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}