{"id":"W1683627990","doi":"10.1002/em.21983","title":"Potent mutagenicity in the Ames test of 2‐cyano‐4‐nitroaniline and 2,6‐dicyano‐4‐nitroaniline, components of disperse dyes","year":2015,"lang":"en","type":"article","venue":"Environmental and Molecular Mutagenesis","topic":"bioluminescence and chemiluminescence research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Ames test; Nitroreductase; Chemistry; Mutagen; Genotoxicity; Nitroaniline; Carcinogen; Stereochemistry; Enzyme; Biochemistry; Organic chemistry; Genetics; Salmonella; Toxicity; Biology; Bacteria","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000283034,0.00019609,0.0002356158,0.00005482476,0.00003910116,0.00001006504,0.000223303,0.0001187063,0.000008218342],"category_scores_gemma":[0.00006414342,0.0001503828,0.00007617362,0.00008723366,0.0005286419,0.000009800551,0.0002337774,0.00009125954,0.000002228388],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000139873,"about_ca_system_score_gemma":0.00002294524,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001140925,"about_ca_topic_score_gemma":0.0000147944,"domain_scores_codex":[0.9987261,0.00009360896,0.0002929711,0.0003413372,0.0003061847,0.000239787],"domain_scores_gemma":[0.9994449,0.00002492631,0.0000950249,0.0003004406,0.00001793217,0.0001167926],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007540979,0.0003106206,0.1222904,0.00003804516,0.00002516199,0.00001638451,0.0001449261,0.000003426673,0.8758397,0.00000517819,0.00003079053,0.00121992],"study_design_scores_gemma":[0.0008879799,0.0003973316,0.0987832,0.00002068928,0.00003852142,0.00003728281,0.001741926,0.00009073097,0.8973751,0.00002019956,0.0004308751,0.0001761755],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9965158,0.002849519,0.00006516829,0.0001553085,0.00001678945,0.0002354004,0.0000567925,0.000002658034,0.0001025566],"genre_scores_gemma":[0.9983241,0.001010025,0.0002405732,0.0001304224,0.00003114065,0.00001751808,0.0001565476,0.00001661192,0.00007309175],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02350721,"threshold_uncertainty_score":0.6132432,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01248040118765739,"score_gpt":0.2307513138479775,"score_spread":0.2182709126603201,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}