{"id":"W1683627990","doi":"10.1002/em.21983","title":"Potent mutagenicity in the Ames test of 2‐cyano‐4‐nitroaniline and 2,6‐dicyano‐4‐nitroaniline, components of disperse dyes","year":2015,"lang":"en","type":"article","venue":"Environmental and Molecular Mutagenesis","topic":"bioluminescence and chemiluminescence research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Ames test; Nitroreductase; Chemistry; Mutagen; Genotoxicity; Nitroaniline; Carcinogen; Stereochemistry; Enzyme; Biochemistry; Organic chemistry; Genetics; Salmonella; Toxicity; Biology; Bacteria","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001118794,0.001307766,0.0005454263,0.0008741678,0.0002836913,0.0002947842,0.0004129719,0.0006927269,0.001674838],"category_scores_gemma":[0.0008126113,0.0003749312,0.0004973036,0.0005298256,0.0004956727,0.0002232209,0.0004813874,0.0006253025,0.0004510565],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002352879,"about_ca_system_score_gemma":0.0003664755,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001077001,"about_ca_topic_score_gemma":0.001972377,"domain_scores_codex":[0.9982864,0.0006325048,0.0001448732,0.000339064,0.0004605135,0.0001366264],"domain_scores_gemma":[0.9985936,0.0005603678,0.0002617202,0.0001982992,0.0002363041,0.0001496245],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005119105,0.00004031981,0.0002574338,0.0000385087,0.00000888082,0.00002118572,0.00002912095,0.00003851201,0.999082,0.00002704613,0.00000828032,0.0003974173],"study_design_scores_gemma":[0.000004985978,0.0009726884,0.002204947,0.000004774425,0.00002027408,0.000104949,0.00002498358,0.0001400889,0.9960715,0.0000179898,0.0004289797,0.000003805175],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9800771,0.00176456,0.01484038,0.00007118234,0.00006538015,0.0001965203,0.0003558519,0.0001231575,0.002505696],"genre_scores_gemma":[0.9660568,0.001993343,0.02077834,0.00006893594,0.00003186558,0.0002627953,0.001298416,0.00007398547,0.009435587],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001674838,"threshold_uncertainty_score":0.005916834,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01248040118765739,"score_gpt":0.2307513138479775,"score_spread":0.2182709126603201,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}