{"id":"W1686747255","doi":"10.1002/mds.25833","title":"A Novel <i>DCTN1</i> mutation with late‐onset parkinsonism and frontotemporal atrophy","year":2014,"lang":"en","type":"article","venue":"Movement Disorders","topic":"Parkinson's Disease Mechanisms and Treatments","field":"Medicine","cited_by":44,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Parkinsonism; Dynactin; Frontotemporal dementia; Atrophy; Neurodegeneration; Amyotrophic lateral sclerosis; Proband; Progressive supranuclear palsy; Mutation; Pathology; Neuroscience; Biology; Medicine; Genetics; Disease; Gene; Dementia; Protein subunit","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001998893,0.001266964,0.0004699483,0.0004845213,0.0008819686,0.000359325,0.0005284794,0.001493677,0.001665413],"category_scores_gemma":[0.0005285776,0.0002949943,0.0003997941,0.0003179817,0.0008186552,0.000252345,0.0004704198,0.0006570657,0.0004967779],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005615997,"about_ca_system_score_gemma":0.0004500721,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003078099,"about_ca_topic_score_gemma":0.00451097,"domain_scores_codex":[0.9998087,0.00001356131,0.00002260409,0.0000877005,0.00003498873,0.00003236475],"domain_scores_gemma":[0.9995803,0.0000824341,0.0001325919,0.00001294584,0.00003384954,0.0001578078],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"case_report","study_design_gemma":"case_report","study_design_scores_codex":[0.0003218813,0.0002128672,0.02174217,0.0001361063,0.00006381408,0.8496768,0.0005169958,0.0002770343,0.120134,0.0006159406,0.001121201,0.00518121],"study_design_scores_gemma":[0.0001030278,0.000459981,0.06264122,0.00004041343,0.0001097464,0.9196946,0.0001300085,0.0007721498,0.01203855,0.0002642484,0.003707629,0.00003848344],"study_design_candidate":"case_report","study_design_consensus":"case_report","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9929764,0.0004117071,0.001359541,0.0004675533,0.00009737693,0.00007581193,0.0002278836,0.00007308527,0.004310617],"genre_scores_gemma":[0.9967178,0.0001105805,0.001265863,0.0003327878,0.00007046249,0.00001429745,0.0001606412,0.00002124458,0.001306296],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003078099,"threshold_uncertainty_score":0.006120384,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006728243280467171,"score_gpt":0.2164760033756378,"score_spread":0.2097477600951706,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}