{"id":"W1687423944","doi":"10.1046/j.1432-1327.2001.02388.x","title":"Alternate routes to conformational specificity in a Greek key β barrel protein","year":2001,"lang":"en","type":"article","venue":"European Journal of Biochemistry","topic":"Protein Structure and Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Ontario Institute for Cancer Research","funders":"National Cancer Institute; Canadian Institutes of Health Research","keywords":"Myxococcus xanthus; Molten globule; Chemistry; Biophysics; Calcium; Folding (DSP implementation); Binding domain; Protein folding; Crystallography; Side chain; Folding funnel; Protein structure; Native state; Domain (mathematical analysis); Biochemistry; Binding site; Phi value analysis; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004426224,0.0001513742,0.0001482901,0.00006074406,0.00003297829,0.00003766942,0.0003711733,0.00004960414,0.00003144243],"category_scores_gemma":[0.0001366937,0.0001387111,0.00009512937,0.0001039937,0.00004292491,0.00000911931,0.0001083429,0.0001983593,0.0000176761],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000282455,"about_ca_system_score_gemma":0.00007931719,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002796026,"about_ca_topic_score_gemma":0.000002881255,"domain_scores_codex":[0.9988989,0.00006870071,0.0004629463,0.0001671113,0.0001982478,0.0002040496],"domain_scores_gemma":[0.9992442,0.000004470578,0.0002331524,0.0002138787,0.000143208,0.0001611369],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003361347,0.0000427368,0.002019516,0.00001816552,0.0000300348,0.0004796199,0.00006915003,0.000236562,0.9923678,0.00002235229,0.000867266,0.003510652],"study_design_scores_gemma":[0.002029448,0.0005288313,0.007857209,0.000208685,0.00001305256,0.003040877,0.0001561591,0.00009680253,0.94025,0.0001959822,0.04514157,0.0004813533],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9851763,0.0002853259,0.004578215,0.0002907955,0.00009018784,0.00009659557,0.00001452028,0.000004474236,0.0094636],"genre_scores_gemma":[0.994962,0.00004517905,0.003459683,0.0002817692,0.0005666772,0.000001391763,0.00002430386,0.00001949457,0.0006395226],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05211778,"threshold_uncertainty_score":0.5656474,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007184728172588338,"score_gpt":0.2184693427658115,"score_spread":0.2112846145932232,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}