{"id":"W16929432","doi":"10.1023/a:1023398130945","title":"In-situ Analysis of Cellular Poly(ADP-ribose) Production in Scrapie-infected Mouse Neuroblastoma Cells","year":2002,"lang":"en","type":"article","venue":"The Histochemical Journal","topic":"Prion Diseases and Protein Misfolding","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université Laval","funders":"","keywords":"Scrapie; Biology; Oxidative stress; Cell culture; NAD+ kinase; Poly ADP ribose polymerase; Molecular biology; ADP-ribosylation; Programmed cell death; Apoptosis; Biochemistry; Enzyme; Polymerase; Prion protein","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003661734,0.0006704744,0.000516448,0.0005191687,0.0007009873,0.000668266,0.0004427944,0.0003818241,0.001678896],"category_scores_gemma":[0.0001727963,0.0003477633,0.0004867372,0.0005489309,0.0004659746,0.0004274556,0.0003103799,0.00133571,0.0009125968],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005551301,"about_ca_system_score_gemma":0.0003987401,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002575223,"about_ca_topic_score_gemma":0.003482177,"domain_scores_codex":[0.9997597,0.00003329103,0.00002826882,0.0000629791,0.00005133611,0.00006438376],"domain_scores_gemma":[0.9995999,0.0001214528,0.00005506249,0.0000676221,0.00007550643,0.0000804139],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006343797,0.00001354127,0.0000671077,0.00003009235,0.00000445362,0.00005407426,0.00003276853,0.00002670605,0.9992023,0.0001545951,0.00002034134,0.0003306182],"study_design_scores_gemma":[0.000007786211,0.00006197147,0.001644761,0.000003526907,0.00001872898,0.0001229112,0.00004747694,0.0004687983,0.9965277,0.00006014781,0.00103301,0.000002986056],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9384782,0.003240447,0.04597636,0.000361269,0.0002345393,0.0001258612,0.002434462,0.0004491409,0.008699802],"genre_scores_gemma":[0.940591,0.003171618,0.04003035,0.0001047785,0.00007674982,0.0002284358,0.002008111,0.0002078908,0.01358104],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002575223,"threshold_uncertainty_score":0.005616426,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008507002392904674,"score_gpt":0.2196777437590312,"score_spread":0.2111707413661265,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}