{"id":"W1693624294","doi":"10.1002/bip.22663","title":"Proline‐poor hydrophobic domains modulate the assembly and material properties of polymeric elastin","year":2015,"lang":"en","type":"article","venue":"Biopolymers","topic":"Connective tissue disorders research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":37,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Hospital for Sick Children","funders":"Canadian Institutes of Health Research; Heart and Stroke Foundation of Canada","keywords":"Elastin; Tropoelastin; Chemistry; Monomer; Elastomer; Biophysics; Hydrophobic effect; Polymer; Extracellular matrix; Biochemistry; Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001711874,0.0001383509,0.0001386459,0.00004583829,0.00006505195,0.00002356842,0.0001887682,0.00008063455,0.00001127659],"category_scores_gemma":[0.00008325893,0.0000939684,0.00004283872,0.000114958,0.0003616872,0.000004456761,0.0001828696,0.00005365706,0.000005293463],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000009870837,"about_ca_system_score_gemma":0.0001210641,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003617989,"about_ca_topic_score_gemma":0.00003551911,"domain_scores_codex":[0.9990524,0.00009984264,0.0001589988,0.0002596926,0.0001819273,0.0002471271],"domain_scores_gemma":[0.9995052,0.000005918602,0.00006590162,0.0002548636,0.00007567886,0.00009241526],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003555369,0.00003625646,0.0004288335,0.00001964803,0.00004690257,0.000001638987,0.0001256166,0.000003593693,0.9965889,0.00002340654,0.0001940616,0.002175575],"study_design_scores_gemma":[0.0005996555,0.0003986824,0.0004210013,0.00001036959,0.0000141957,0.000019532,0.0005456277,0.0001989507,0.9960138,0.00001550204,0.00162833,0.0001343216],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9948252,0.003831379,0.00002949116,0.0004181566,0.0001318989,0.0002802477,0.00001799248,0.00000969245,0.0004559405],"genre_scores_gemma":[0.9990298,0.00008675091,0.00003478724,0.00005427106,0.0001168844,0.00003403548,0.00001557916,0.0000231522,0.0006047597],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004204579,"threshold_uncertainty_score":0.383192,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02389624397120269,"score_gpt":0.2593570167011913,"score_spread":0.2354607727299886,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}