{"id":"W1698712530","doi":"10.18632/aging.100556","title":"Metformin, aging and cancer","year":2013,"lang":"en","type":"editorial","venue":"Aging","topic":"Telomeres, Telomerase, and Senescence","field":"Medicine","cited_by":44,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"","keywords":"Metformin; Cancer; Inflammation; Senescence; Cancer cell; Chemokine; Medicine; Biology; Cancer research; Immunology; Internal medicine; Endocrinology; Diabetes mellitus","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001973065,0.0003281544,0.000599718,0.0001991826,0.0001242815,0.00007929191,0.0001333362,0.0003578726,0.000244883],"category_scores_gemma":[0.0002821498,0.0002809505,0.00008206827,0.0001505866,0.00008957891,0.0001597267,0.0001024979,0.0008168912,0.00006082805],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001245057,"about_ca_system_score_gemma":0.0003143879,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002994343,"about_ca_topic_score_gemma":0.0000778562,"domain_scores_codex":[0.9981636,0.00002226498,0.0002968248,0.0005001796,0.0005632475,0.0004538923],"domain_scores_gemma":[0.998788,0.0002766444,0.0001474315,0.0003603872,0.0002050196,0.0002225054],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001003287,0.00001259231,0.001207456,0.0004963171,0.00009195404,0.00008895795,0.0004630844,2.170433e-7,0.0003234819,0.000007567834,0.9161611,0.08113727],"study_design_scores_gemma":[0.0006433508,0.00003158125,0.0004708412,0.001152293,0.0002272104,0.00001938649,0.0001351591,0.00004669447,0.0004543859,0.00002909695,0.9964731,0.0003168648],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"editorial","genre_gemma":"editorial","genre_scores_codex":[0.01576144,0.03228284,0.00003725763,0.0008922541,0.9479918,0.0004756192,0.00004562612,0.0002216225,0.00229155],"genre_scores_gemma":[0.006090502,0.01235297,0.0004897465,0.0004251162,0.9669362,0.00007330025,0.0001537207,0.0001060112,0.01337239],"genre_candidate":"editorial","genre_consensus":"editorial","teacher_disagreement_score":0.0808204,"threshold_uncertainty_score":0.9999642,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01285294789570173,"score_gpt":0.299381402321843,"score_spread":0.2865284544261412,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}