{"id":"W1700971463","doi":"10.1046/j.1365-2125.2003.01825.x","title":"Lack of pharmacokinetic interaction between retigabine and phenobarbitone at steady‐state in healthy subjects","year":2003,"lang":"en","type":"article","venue":"British Journal of Clinical Pharmacology","topic":"Pharmacological Receptor Mechanisms and Effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":47,"is_retracted":false,"has_abstract":true,"ca_institutions":"Women's Health Research Institute","funders":"","keywords":"Pharmacokinetics; Pharmacology; Anticonvulsant; Phenobarbital; Carbamazepine; Metabolite; Chemistry; Active metabolite; Oral administration; Medicine; Internal medicine; Epilepsy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003849668,0.0002774614,0.0004439392,0.0001583314,0.0003121953,0.0003414062,0.00009941981,0.0003163766,0.001370012],"category_scores_gemma":[0.0007917496,0.0001697502,0.0001633225,0.0001055993,0.0002087051,0.000168079,0.0001020696,0.0002572091,0.0003724548],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001942787,"about_ca_system_score_gemma":0.0001821219,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002406938,"about_ca_topic_score_gemma":0.002116826,"domain_scores_codex":[0.9997374,0.00006743903,0.00001634868,0.00008590751,0.00005859724,0.00003427158],"domain_scores_gemma":[0.9997117,0.00008376834,0.00007801726,0.00002827005,0.00003173114,0.00006646336],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.01440611,0.001197652,0.8750243,0.000134042,0.0005395666,0.002271654,0.0006380609,0.0003907091,0.06748254,0.0001381003,0.0006574157,0.03711988],"study_design_scores_gemma":[0.0001505387,0.006529497,0.987163,0.00000469837,0.0001420497,0.002224691,0.00007466412,0.0005299028,0.002286154,0.00004954591,0.0008362125,0.000009122595],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9988354,0.0004184438,0.0001858975,0.0000142617,0.000004532532,0.00001443803,0.00008346065,0.00001257286,0.0004310877],"genre_scores_gemma":[0.9992381,0.0001125611,0.0001130632,0.00004520753,0.000009327908,0.000008336053,0.0001492323,0.000002874287,0.0003212735],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002406938,"threshold_uncertainty_score":0.004785895,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06827370664692188,"score_gpt":0.4242591758030635,"score_spread":0.3559854691561417,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}