{"id":"W1701032485","doi":"10.4049/jimmunol.169.2.702","title":"Phagocytosis of Apoptotic Cells by Macrophages Induces Novel Signaling Events Leading to Cytokine-Independent Survival and Inhibition of Proliferation: Activation of Akt and Inhibition of Extracellular Signal-Regulated Kinases 1 and 2","year":2002,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Phagocytosis and Immune Regulation","field":"Immunology and Microbiology","cited_by":112,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Montreal General Hospital","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute","keywords":"Cell biology; MAPK/ERK pathway; Protein kinase B; Kinase; Apoptosis; Biology; Cytokine; Signal transduction; Phagocytosis; Extracellular; Cancer research; Immunology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002501288,0.0003929302,0.0002315614,0.0002308348,0.0001643222,0.0003298076,0.0001455511,0.0002817307,0.0005872776],"category_scores_gemma":[0.0001322961,0.0001555169,0.0002748184,0.00009820254,0.0003201838,0.0002619445,0.0002170776,0.0004784491,0.0001941254],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002013448,"about_ca_system_score_gemma":0.0002062181,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008928128,"about_ca_topic_score_gemma":0.0002090303,"domain_scores_codex":[0.9997842,0.00005222728,0.000014657,0.00002111405,0.00005030236,0.00007756517],"domain_scores_gemma":[0.9999005,0.00002338003,0.00003237726,0.00001034548,0.00001305241,0.00002025997],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004145982,0.0001014436,0.0003581218,0.0001094315,0.000008868496,0.0001806066,0.00002311579,0.00008536964,0.9942533,0.000281731,0.00005043725,0.004132949],"study_design_scores_gemma":[0.0000885444,0.001077426,0.00621151,0.00001445907,0.00002559666,0.0008689132,0.00003959218,0.0007932271,0.9883347,0.0002463877,0.002293092,0.000006543849],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.987187,0.007228605,0.003876323,0.0001332503,0.0000409353,0.0000326094,0.00005840038,0.00005023981,0.001392704],"genre_scores_gemma":[0.992754,0.003770646,0.002294526,0.00005536294,0.00002871192,0.00003494105,0.0001094981,0.000005377007,0.0009467911],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005872776,"threshold_uncertainty_score":0.001964688,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02006274177341098,"score_gpt":0.2306470920132148,"score_spread":0.2105843502398038,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}