{"id":"W1701032485","doi":"10.4049/jimmunol.169.2.702","title":"Phagocytosis of Apoptotic Cells by Macrophages Induces Novel Signaling Events Leading to Cytokine-Independent Survival and Inhibition of Proliferation: Activation of Akt and Inhibition of Extracellular Signal-Regulated Kinases 1 and 2","year":2002,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Phagocytosis and Immune Regulation","field":"Immunology and Microbiology","cited_by":112,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Montreal General Hospital","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute","keywords":"Cell biology; MAPK/ERK pathway; Protein kinase B; Kinase; Apoptosis; Biology; Cytokine; Signal transduction; Phagocytosis; Extracellular; Cancer research; Immunology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007872875,0.0001792011,0.0006063724,0.0003090283,0.0001049128,0.000006183064,0.00009068344,0.000221257,0.00005023112],"category_scores_gemma":[0.00007442971,0.0001423915,0.00006504293,0.0002005071,0.0003224392,0.0002750749,0.00008031251,0.0002181163,5.549288e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003140283,"about_ca_system_score_gemma":0.00002395267,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005139838,"about_ca_topic_score_gemma":0.000001959756,"domain_scores_codex":[0.9981596,0.0003882297,0.001012153,0.0001437935,0.0001173954,0.0001788516],"domain_scores_gemma":[0.9977862,0.0002952335,0.001432953,0.0001286181,0.0003378118,0.00001915564],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006847311,0.0003335594,0.0004096828,0.0001021845,0.000321409,4.272332e-7,0.001346097,0.0002102719,0.9944808,0.00008207132,0.00001706919,0.002011636],"study_design_scores_gemma":[0.00215702,0.001366041,0.005848384,0.0004264791,0.0001768493,0.00008415432,0.000718454,0.00003852844,0.9889817,0.00008787107,0.000007945946,0.0001065529],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9892977,0.008733394,0.001401903,0.0001573413,0.0001007026,0.0002689928,0.00002997942,0.000004006213,0.000005950218],"genre_scores_gemma":[0.9990519,0.0007650676,0.00009305227,0.000007276165,0.0000150158,0.000002444981,0.00001630889,0.00001337134,0.00003559437],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009754137,"threshold_uncertainty_score":0.5806558,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02006274177341098,"score_gpt":0.2306470920132148,"score_spread":0.2105843502398038,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}