{"id":"W1701541921","doi":"10.1155/2012/957973","title":"Breakthrough Filamentous Fungal Infections in Pediatric Hematopoetic Stem Cell Transplant and Oncology Patients Receiving Caspofungin","year":2012,"lang":"en","type":"article","venue":"Canadian Journal of Infectious Diseases and Medical Microbiology","topic":"Antifungal resistance and susceptibility","field":"Medicine","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; Pediatric Oncology Group; University of Toronto","funders":"","keywords":"Caspofungin; Voriconazole; Medicine; Posaconazole; Echinocandin; Internal medicine; Aspergillosis; Hematopoietic stem cell transplantation; Salvage therapy; Transplantation; Surgery; Antifungal; Immunology; Chemotherapy; Dermatology; Fluconazole","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003959134,0.0002223292,0.0003641699,0.000708625,0.0004591888,0.0005373642,0.0003233147,0.0004259033,0.00130417],"category_scores_gemma":[0.001643667,0.0001741422,0.000298007,0.001090262,0.0003275887,0.000381055,0.0002865496,0.0004095228,0.0001932642],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007773553,"about_ca_system_score_gemma":0.0007802575,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006101545,"about_ca_topic_score_gemma":0.007507429,"domain_scores_codex":[0.9995773,0.00003743127,0.00005401836,0.0000601462,0.000134003,0.0001370844],"domain_scores_gemma":[0.9978439,0.0003390846,0.001196517,0.00005493023,0.000226082,0.0003394838],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0001106367,0.00001521677,0.9856516,0.00004706679,0.00001533112,0.008771224,0.0002235939,0.00003543979,0.0004886606,0.00001776151,0.0002325252,0.004390933],"study_design_scores_gemma":[0.00001440885,0.0002389097,0.9232108,0.00006147481,0.00004670379,0.07318582,0.0007486815,0.0001132272,0.0006819371,0.00002127927,0.001670971,0.000005778244],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9956923,0.003421132,0.00009637932,0.00005325994,0.000007777843,0.00001275193,0.0001764645,0.000006100813,0.0005337585],"genre_scores_gemma":[0.9980173,0.001395109,0.0001216562,0.00004227595,0.00001897348,0.000005654054,0.0003189917,0.0000026818,0.00007733703],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006101545,"threshold_uncertainty_score":0.01213205,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006575802248126498,"score_gpt":0.2354719333350555,"score_spread":0.228896131086929,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}