{"id":"W1701915267","doi":"10.1007/s00726-015-2113-z","title":"Soluble expression, purification and functional characterization of a coil peptide composed of a positively charged and hydrophobic motif","year":2015,"lang":"en","type":"article","venue":"Amino Acids","topic":"Chemical Synthesis and Analysis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal; Polytechnique Montréal","funders":"Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs","keywords":"Peptide; Chemistry; Motif (music); Coiled coil; Proteomics; Biochemistry; Biophysics; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008563455,0.00006636266,0.0001253416,0.00002484357,0.000021883,0.000005634815,0.00003281709,0.0000629608,0.000008778919],"category_scores_gemma":[0.00003296266,0.00005941012,0.00002964209,0.0000477696,0.00009030301,0.00000555426,0.00003871543,0.00002196745,6.109246e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000003984511,"about_ca_system_score_gemma":0.00001690548,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001138272,"about_ca_topic_score_gemma":8.212334e-7,"domain_scores_codex":[0.999513,0.0000258826,0.0001536993,0.0001571638,0.00008731242,0.00006288793],"domain_scores_gemma":[0.9996222,0.000007384222,0.0001105922,0.00009972677,0.0001063043,0.00005384524],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006742299,0.00005100528,0.0102838,0.00001605525,0.00002248335,9.257339e-8,0.00005663574,7.921964e-7,0.9889392,0.00001104566,0.00004907808,0.000502333],"study_design_scores_gemma":[0.0003261604,0.00006618421,0.07011808,0.00001566264,0.00002290467,0.000002124842,0.00003714717,0.000169276,0.9287568,0.0000148286,0.000411337,0.00005949393],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.998879,0.0001632231,0.0007208312,0.00005474687,0.00001484043,0.0000500564,0.00001933609,0.000002715615,0.00009530996],"genre_scores_gemma":[0.9991929,0.00008699201,0.0001857201,0.00002273098,0.00003514408,0.000005769505,0.0002703647,0.000005712385,0.0001946573],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06018246,"threshold_uncertainty_score":0.2422674,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01359746776559018,"score_gpt":0.2101158630935678,"score_spread":0.1965183953279777,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}