{"id":"W1704268275","doi":"10.1139/o11-031","title":"Insulation of tumor suppressor genes by the nuclear factor CTCF","year":2011,"lang":"en","type":"article","venue":"Biochemistry and Cell Biology","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Dirección General de Asuntos del Personal Académico, Universidad Nacional Autónoma de México; Consejo Nacional de Ciencia y Tecnología","keywords":"CTCF; Chromatin; Biology; Epigenetics; Genetics; Insulator (electricity); Histone; DNA methylation; Gene; Gene silencing; Transcription factor; Gene expression; Enhancer","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008976345,0.0001526144,0.0001545683,0.0001925434,0.0001373434,0.0003210191,0.0001657193,0.0001677717,0.001249193],"category_scores_gemma":[0.0003056096,0.00008917935,0.000143739,0.0001174113,0.000207134,0.00017357,0.0003546689,0.0002955102,0.000452769],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002894632,"about_ca_system_score_gemma":0.0001654282,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008666852,"about_ca_topic_score_gemma":0.0007292159,"domain_scores_codex":[0.9998767,0.00001695832,0.000005922696,0.00002478945,0.00003941833,0.00003603952],"domain_scores_gemma":[0.9998753,0.00002272879,0.00002819115,0.00002513085,0.00001656069,0.00003197756],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004870862,0.000006750437,0.0003762557,0.00001900635,0.000002018978,0.0001066671,0.0000223494,0.00009654844,0.9937669,0.0006448898,0.00005763802,0.004852354],"study_design_scores_gemma":[0.00002718631,0.0001240592,0.006899989,0.000008283381,0.000008634623,0.0007647977,0.00004844197,0.002198481,0.9779186,0.001119079,0.01087482,0.000007759263],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9775689,0.003777847,0.01327147,0.0001441378,0.00003939811,0.0000128711,0.0001593535,0.0003746564,0.004651403],"genre_scores_gemma":[0.9971194,0.0003337309,0.0007398519,0.00002375514,0.000005128343,0.000004511367,0.0001108789,0.00002003822,0.001642759],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001249193,"threshold_uncertainty_score":0.004178941,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01350365591915214,"score_gpt":0.2205536864150178,"score_spread":0.2070500304958656,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}