{"id":"W1706011315","doi":"10.3390/cells4030387","title":"Nuclear Import of Yeast Proteasomes","year":2015,"lang":"en","type":"review","venue":"Cells","topic":"Ubiquitin and proteasome pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Proteasome; Nuclear transport; Importin; Cell biology; Cytoplasm; Karyopherin; Biology; Nuclear pore; Yeast; Saccharomyces cerevisiae; Organelle; Nuclear localization sequence; Cell nucleus; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000255299,0.0002699345,0.0007932628,0.00004843502,0.00002096668,0.00001185722,0.0003471116,0.0004055891,0.0001006711],"category_scores_gemma":[0.00002607887,0.0002237498,0.0003590266,0.00008057323,0.00007740723,0.000001217401,0.0001911725,0.0001469868,0.0002075675],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001400833,"about_ca_system_score_gemma":0.0003358383,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003695395,"about_ca_topic_score_gemma":4.831869e-7,"domain_scores_codex":[0.9988605,0.00008803665,0.000361875,0.0003378683,0.0001456823,0.0002060608],"domain_scores_gemma":[0.9989645,0.000003828612,0.0003053626,0.0005327028,0.00007539942,0.0001181474],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001699761,0.000114252,0.000001729692,0.01436295,0.0002282268,0.0000119354,0.00005159601,2.650632e-7,0.01171115,0.00008151798,0.02879647,0.9446229],"study_design_scores_gemma":[0.00009319863,0.0001364954,1.377533e-7,0.000929088,0.0001134691,0.00002104666,0.000007220905,2.419074e-7,0.0118834,0.00001371768,0.9865663,0.0002356736],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001083148,0.9902977,0.000003470725,0.000002084013,0.0001871435,0.0007336738,0.0001734576,0.00001207281,0.008482036],"genre_scores_gemma":[0.00005214495,0.9962295,0.000262394,0.00001836083,0.0003488713,0.00005061256,0.0002558156,0.0000729837,0.002709335],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9577699,"threshold_uncertainty_score":0.9124252,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04106848820806044,"score_gpt":0.3016673708666623,"score_spread":0.2605988826586019,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}