{"id":"W171017649","doi":"10.1023/a:1014596924446","title":"Selective cytotoxicity of scFv-TNF fusion protein on the tumor cells","year":2002,"lang":"en","type":"article","venue":"Biotechnology Letters","topic":"Monoclonal and Polyclonal Antibodies Research","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":false,"ca_institutions":"KMT Hepatech (Canada); University of Alberta","funders":"","keywords":"Pichia pastoris; Fusion protein; Tumor necrosis factor alpha; Cell culture; Molecular biology; Biology; Chemistry; Recombinant DNA; Immunology; Gene; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000152129,0.0001457421,0.0002418446,0.0001935328,0.0001185825,0.000004673272,0.0002236895,0.0001691788,0.0003490142],"category_scores_gemma":[0.0001029706,0.0000879304,0.0001017161,0.0003717591,0.0005707329,0.00001729437,0.00009556999,0.0006437851,0.0002440241],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005251718,"about_ca_system_score_gemma":0.00001283865,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007652128,"about_ca_topic_score_gemma":0.000004474609,"domain_scores_codex":[0.9988642,0.00006518906,0.0001921646,0.0002579961,0.0002959104,0.0003245136],"domain_scores_gemma":[0.9993876,0.00009407514,0.00008031075,0.0003446755,0.0000423468,0.00005105763],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001690072,0.0001516388,0.0002635775,0.00004240431,0.00004601135,0.0000658569,0.00005279742,0.000001009335,0.9838399,0.001523512,0.01198967,0.00185457],"study_design_scores_gemma":[0.0003343502,0.00056517,0.00202014,0.00008671207,0.00001039206,0.00004534223,0.00003155076,0.0001948666,0.9911534,0.00006309438,0.005405417,0.00008958112],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8751059,0.00007440824,0.00003122748,0.1230384,0.00003613496,0.000626119,0.00001360709,0.00006776828,0.001006401],"genre_scores_gemma":[0.9937331,0.00003716503,0.0003939758,0.004918405,0.00006888718,0.00003955775,0.000002239723,0.00001387118,0.000792781],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1186272,"threshold_uncertainty_score":0.382146,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02383916568300462,"score_gpt":0.2483034217339698,"score_spread":0.2244642560509651,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}