{"id":"W1711202046","doi":"10.1016/j.scr.2015.09.009","title":"Reprogramming of mouse amniotic fluid cells using a PiggyBac transposon system","year":2015,"lang":"en","type":"article","venue":"Stem Cell Research","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital","funders":"Great Ormond Street Hospital Charity; Great Ormond Street Hospital for Children; National Institute for Health and Care Research; Fondazione Cassa di Risparmio di Padova e Rovigo","keywords":"Biology; Induced pluripotent stem cell; Reprogramming; Cell biology; KOSR; Somatic cell; Germ layer; Amniotic fluid; Embryonic stem cell; Molecular biology; Transposable element; Stem cell; Cell; Genetics; Fetus; Genome; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005011167,0.0006172165,0.0004423658,0.0006863817,0.0002939841,0.000500172,0.0005209587,0.0005527873,0.001542686],"category_scores_gemma":[0.0002911843,0.0002194213,0.0004756656,0.0002836161,0.0003581646,0.0002825287,0.0005687949,0.0007609871,0.001196256],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002012738,"about_ca_system_score_gemma":0.0003722491,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004183985,"about_ca_topic_score_gemma":0.0003860861,"domain_scores_codex":[0.9995854,0.00008459496,0.000056577,0.00009368248,0.0001300871,0.00004956136],"domain_scores_gemma":[0.9998769,0.00002739918,0.00003134213,0.00003111317,0.00001402144,0.00001914784],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003395652,0.00001605653,0.00009363765,0.00003871456,0.00000474373,0.0001268279,0.00002776669,0.00005235357,0.9960893,0.0002718461,0.0000487922,0.003195994],"study_design_scores_gemma":[0.00002232788,0.0001749411,0.001166811,0.00001831226,0.00003647641,0.0006982143,0.00002359916,0.0006638111,0.9827204,0.0001324903,0.01433312,0.000009436025],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7753491,0.006575001,0.1941894,0.0005242066,0.0008884026,0.001349817,0.00272972,0.00160961,0.01678457],"genre_scores_gemma":[0.8783571,0.005169302,0.09591909,0.0003069283,0.0001030743,0.0008876735,0.002637917,0.0002145901,0.01640433],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001542686,"threshold_uncertainty_score":0.005160809,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09762341791349348,"score_gpt":0.3441697847932682,"score_spread":0.2465463668797747,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}