{"id":"W1717642344","doi":"10.1002/0471142735.im0205s102","title":"Production of Monoclonal Antibodies","year":2013,"lang":"en","type":"article","venue":"Current Protocols in Immunology","topic":"Monoclonal and Polyclonal Antibodies Research","field":"Medicine","cited_by":111,"is_retracted":false,"has_abstract":true,"ca_institutions":"Stemcell Technologies","funders":"","keywords":"Monoclonal antibody; Cloning (programming); Molecular biology; Antibody; Immunization; Biology; Cell culture; Limiting; Hybridoma technology; Selection (genetic algorithm); Chemistry; Computational biology; Immunology; Genetics; Computer science","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002052235,0.00174664,0.001738667,0.00292415,0.0008457135,0.001665033,0.002647869,0.001238049,0.02411044],"category_scores_gemma":[0.001428731,0.001336037,0.001305016,0.001489466,0.0003456115,0.0009086195,0.001482869,0.003511146,0.03861051],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009642609,"about_ca_system_score_gemma":0.0008345879,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004458546,"about_ca_topic_score_gemma":0.0008917213,"domain_scores_codex":[0.9979295,0.0002939106,0.0002460614,0.0003890847,0.0008368327,0.0003047342],"domain_scores_gemma":[0.9988737,0.0001612339,0.00007612665,0.0003085656,0.0003692308,0.0002111401],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002103754,0.0002792664,0.0003766904,0.0007372103,0.00007939419,0.0002314809,0.00009009754,0.0003181827,0.9044959,0.002855544,0.02044925,0.06987657],"study_design_scores_gemma":[0.0002140736,0.0007304375,0.001409138,0.0002306896,0.0001175937,0.0008248196,0.00003770061,0.0009229769,0.3874799,0.001046683,0.6069344,0.00005163437],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"methods","genre_scores_codex":[0.108609,0.05108501,0.5118212,0.00422762,0.009788188,0.01472177,0.04882807,0.02015236,0.2307668],"genre_scores_gemma":[0.1504184,0.04427533,0.4876268,0.003134146,0.00228558,0.01241805,0.1403239,0.002305752,0.1572122],"genre_candidate":"methods","genre_consensus":"methods","teacher_disagreement_score":0.02411044,"threshold_uncertainty_score":0.08065742,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06413482919671443,"score_gpt":0.3941101416598194,"score_spread":0.329975312463105,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}