{"id":"W17242150","doi":"10.1007/978-1-59745-443-8_2","title":"Stem Cell Engineering Using Transducible Cre Recombinase","year":2007,"lang":"en","type":"article","venue":"Methods in molecular medicine","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Stem Cell Network","keywords":"Cre-Lox recombination; Cre recombinase; Transduction (biophysics); Biology; Recombinase; Somatic cell; Mutagenesis; Stem cell; Computational biology; Regenerative medicine; Cell biology; Genetics; Molecular biology; Transgene; Mutation; Gene; Recombination; Genetically modified mouse","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001823422,0.0001961025,0.0002485856,0.0001812744,0.00002596771,0.000006134951,0.0002065251,0.0001736569,0.0000332469],"category_scores_gemma":[0.00006247518,0.0001854819,0.0000788231,0.0002525413,0.00005086947,0.000003513729,0.00004843192,0.0001847438,0.000002325353],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002858488,"about_ca_system_score_gemma":0.00003342109,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005326121,"about_ca_topic_score_gemma":0.000008219938,"domain_scores_codex":[0.9986053,0.0001416058,0.0003687094,0.0003874255,0.0001365404,0.0003604373],"domain_scores_gemma":[0.9993398,0.00003842869,0.00006119219,0.0003926608,0.00005583189,0.0001121217],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000350348,0.0000337178,0.0002244757,0.000036246,0.00001666015,0.00009104279,0.0001274741,0.0006217433,0.9844984,0.00002136434,0.00004675969,0.01424701],"study_design_scores_gemma":[0.0007433349,0.0003052534,0.0003156221,0.00008369477,0.00002565961,0.00003107096,0.0002599998,0.0009243321,0.9928711,0.00004608904,0.004188577,0.0002052314],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.4928197,0.002339654,0.5036846,0.00003904757,0.000241544,0.00009066513,6.788453e-7,0.000008263199,0.0007758642],"genre_scores_gemma":[0.6943111,0.0001884885,0.3043171,0.0005569663,0.0001987473,0.000007747529,0.00002124731,0.00005131616,0.0003472901],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.2014914,"threshold_uncertainty_score":0.7563732,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03089713199499638,"score_gpt":0.3588385552657014,"score_spread":0.327941423270705,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}