{"id":"W1725537921","doi":"10.4049/jimmunol.174.12.7497","title":"A New Dynamic Model of CD8+ T Effector Cell Responses via CD4+ T Helper-Antigen-Presenting Cells","year":2005,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":153,"is_retracted":false,"has_abstract":true,"ca_institutions":"Saskatchewan Cancer Agency; University of Saskatchewan","funders":"","keywords":"Priming (agriculture); Cytotoxic T cell; CD28; CD80; CTL*; T cell; Cell biology; Biology; CD8; Antigen-presenting cell; Immunology; MHC class I; MHC class II; Antigen; Immune system; CD40; In vitro; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003274606,0.0004809283,0.0004049773,0.0004190642,0.0002939642,0.0009227607,0.001308467,0.0009815118,0.005506294],"category_scores_gemma":[0.0003216524,0.0002170948,0.0005015724,0.000205877,0.0006732967,0.002148892,0.0004015465,0.0007266101,0.001423231],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007767311,"about_ca_system_score_gemma":0.0004937749,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000438324,"about_ca_topic_score_gemma":0.0002943512,"domain_scores_codex":[0.9997863,0.00004008975,0.000009225171,0.00006206729,0.00006891492,0.00003348104],"domain_scores_gemma":[0.9998865,0.0000363084,0.00001415657,0.0000142938,0.0000253526,0.00002327901],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.0002519443,0.0001406544,0.001125445,0.0005066974,0.00006813336,0.001016699,0.0002945455,0.0901534,0.09000777,0.775562,0.006107442,0.03476524],"study_design_scores_gemma":[0.0001530374,0.0004314258,0.000596205,0.00005427626,0.00006478052,0.0008160099,0.00008404636,0.5257763,0.01071671,0.4274232,0.03384,0.00004402763],"study_design_candidate":"simulation_or_modeling","study_design_consensus":null,"genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.1597423,0.00775333,0.7271272,0.009871628,0.001293269,0.0002586195,0.0005268687,0.001255975,0.09217087],"genre_scores_gemma":[0.8739377,0.005052968,0.05495764,0.001577835,0.0009688656,0.0004497604,0.0003193528,0.0001184488,0.06261733],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.005506294,"threshold_uncertainty_score":0.01842046,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01073138724179926,"score_gpt":0.234160071283192,"score_spread":0.2234286840413928,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}