{"id":"W1725537921","doi":"10.4049/jimmunol.174.12.7497","title":"A New Dynamic Model of CD8+ T Effector Cell Responses via CD4+ T Helper-Antigen-Presenting Cells","year":2005,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":153,"is_retracted":false,"has_abstract":true,"ca_institutions":"Saskatchewan Cancer Agency; University of Saskatchewan","funders":"","keywords":"Priming (agriculture); Cytotoxic T cell; CD28; CD80; CTL*; T cell; Cell biology; Biology; CD8; Antigen-presenting cell; Immunology; MHC class I; MHC class II; Antigen; Immune system; CD40; In vitro; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001209515,0.0003956088,0.0009462333,0.00044387,0.0002779174,0.00001284679,0.00139779,0.0005627116,0.0006262497],"category_scores_gemma":[0.0001187306,0.0002740931,0.0004098886,0.0002466603,0.000664965,0.0001993886,0.000371739,0.001289075,0.000649781],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000960649,"about_ca_system_score_gemma":0.0003601035,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000149247,"about_ca_topic_score_gemma":0.00003614572,"domain_scores_codex":[0.996272,0.001306563,0.001289499,0.0002515316,0.0001026493,0.0007777869],"domain_scores_gemma":[0.9966095,0.001026952,0.001329509,0.0007224691,0.0002679385,0.00004364174],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002385696,0.0003043226,0.0001267908,0.00002017822,0.0006505801,0.00001061745,0.001401438,0.0009764487,0.9862612,0.00005251811,0.001891334,0.005918901],"study_design_scores_gemma":[0.003295692,0.0009330107,0.0003405358,0.00004927504,0.0002402198,0.00111126,0.0003645485,0.0004107423,0.984761,0.0003036217,0.007920669,0.0002694532],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9628103,0.02843024,0.005702621,0.0008482414,0.001453527,0.0002387348,0.00001783348,0.00003710335,0.0004613716],"genre_scores_gemma":[0.9855271,0.002636911,0.001355949,0.0001449826,0.00009131644,0.000002563121,0.00000760124,0.00004743208,0.01018616],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02579333,"threshold_uncertainty_score":0.9999712,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01073138724179926,"score_gpt":0.234160071283192,"score_spread":0.2234286840413928,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}