{"id":"W1740921288","doi":"10.4236/pp.2015.69046","title":"Platelet-Activating Factor Induces Du-al-Specificity Phosphatase 1 and 5 Gene Expression","year":2015,"lang":"en","type":"article","venue":"Pharmacology &amp Pharmacy","topic":"Protein Tyrosine Phosphatases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research","keywords":"Dual-specificity phosphatase; MAPK/ERK pathway; Cell biology; Platelet-activating factor; Kinase; Phosphatase; p38 mitogen-activated protein kinases; Wortmannin; MAPK cascade; Chemistry; Signal transduction; Proinflammatory cytokine; PI3K/AKT/mTOR pathway; Phosphorylation; Biology; Molecular biology; Inflammation; Endocrinology; Immunology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003349731,0.0003948564,0.0003073093,0.00007772174,0.0002203228,0.00005280691,0.0003708984,0.0001247976,0.0003205173],"category_scores_gemma":[0.0001967228,0.0003851961,0.00007081834,0.0001340663,0.0002197922,0.00005250578,0.0005508953,0.0003205346,0.00005369321],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004891762,"about_ca_system_score_gemma":0.0001614508,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007509248,"about_ca_topic_score_gemma":0.000002702286,"domain_scores_codex":[0.9978637,0.0002234123,0.0003759213,0.0007549363,0.0002354925,0.000546605],"domain_scores_gemma":[0.9987467,0.00006521716,0.0002404267,0.0002956173,0.0001645798,0.0004874571],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007323543,0.0001616108,0.001516609,0.00001915296,0.00008452613,0.00003593264,0.0001096532,0.00003715157,0.9122037,0.00001697363,0.07865728,0.006425051],"study_design_scores_gemma":[0.002735674,0.00007620212,0.0001736296,0.000007220215,0.00001260581,0.00005828261,0.00002190107,0.00004534914,0.6831523,0.00002435507,0.3134,0.0002925032],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9734838,0.0226503,0.0009895195,0.0008622218,0.0009125738,0.0005395011,0.0003634356,0.00008308615,0.0001155788],"genre_scores_gemma":[0.9906545,0.001737175,0.003079846,0.002641556,0.001040393,0.0001360066,0.0005762351,0.00005965818,0.00007457556],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2347427,"threshold_uncertainty_score":0.99986,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05408835685338217,"score_gpt":0.3331126235194238,"score_spread":0.2790242666660416,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}