{"id":"W1740921288","doi":"10.4236/pp.2015.69046","title":"Platelet-Activating Factor Induces Du-al-Specificity Phosphatase 1 and 5 Gene Expression","year":2015,"lang":"en","type":"article","venue":"Pharmacology &amp Pharmacy","topic":"Protein Tyrosine Phosphatases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research","keywords":"Dual-specificity phosphatase; MAPK/ERK pathway; Cell biology; Platelet-activating factor; Kinase; Phosphatase; p38 mitogen-activated protein kinases; Wortmannin; MAPK cascade; Chemistry; Signal transduction; Proinflammatory cytokine; PI3K/AKT/mTOR pathway; Phosphorylation; Biology; Molecular biology; Inflammation; Endocrinology; Immunology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001556779,0.0003103903,0.0002137569,0.0003101462,0.0001298166,0.0002242799,0.00008758256,0.0001989132,0.001258412],"category_scores_gemma":[0.0001344605,0.0001709143,0.0004978644,0.0001833038,0.0001561791,0.000113906,0.0002149168,0.0004303954,0.000372724],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002664446,"about_ca_system_score_gemma":0.0001612266,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006811902,"about_ca_topic_score_gemma":0.00100521,"domain_scores_codex":[0.9998024,0.00004222623,0.00001420054,0.0000376705,0.00003746821,0.00006614228],"domain_scores_gemma":[0.9998817,0.00003128658,0.00002279636,0.00001594916,0.00001714054,0.00003108568],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000113318,0.00002501242,0.0001529516,0.00003804487,0.000003624702,0.00005583754,0.0000173944,0.00003043911,0.998245,0.00008838242,0.00004287019,0.001187184],"study_design_scores_gemma":[0.00001898356,0.0005157726,0.01277553,0.000009380576,0.00001609168,0.0003394165,0.00005290979,0.001069525,0.9810901,0.0001175867,0.003990086,0.000004592997],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9867813,0.004110467,0.005693429,0.0001704595,0.00005831689,0.00005785881,0.0007764951,0.00008301007,0.002268573],"genre_scores_gemma":[0.9877207,0.00165278,0.004083109,0.0001613416,0.00002821214,0.00007457185,0.001557596,0.00001660879,0.004704953],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001258412,"threshold_uncertainty_score":0.004209757,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05408835685338217,"score_gpt":0.3331126235194238,"score_spread":0.2790242666660416,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}