{"id":"W1744409238","doi":"10.1016/s1054-3589(00)49024-1","title":"Inhibitors of HIV- I reverse transcriptase","year":2000,"lang":"en","type":"review","venue":"Advances in pharmacology","topic":"HIV/AIDS drug development and treatment","field":"Medicine","cited_by":53,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; Jewish General Hospital","funders":"","keywords":"Reverse transcriptase; Polymerase; DNA polymerase; Biology; DNA; Virology; Nucleoside analogue; Enzyme; Nucleoside Reverse Transcriptase Inhibitor; Nucleoside; RNase H; RNA; Gene; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000136513,0.0003900059,0.001980951,0.0004557034,0.00002201533,0.000001576006,0.0001404578,0.0002285601,0.001917492],"category_scores_gemma":[0.00001010757,0.0003082508,0.0003564621,0.0004728264,0.0001526376,0.0001077769,0.00002195487,0.0004145269,0.0002044756],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001951968,"about_ca_system_score_gemma":0.0003579303,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001938852,"about_ca_topic_score_gemma":0.000002700464,"domain_scores_codex":[0.9980691,0.0001532702,0.0008667168,0.0004100513,0.0001649096,0.0003359524],"domain_scores_gemma":[0.9993149,0.0001366528,0.0002290227,0.0001785047,0.00002566528,0.0001152309],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001052928,0.0004442705,0.00006865178,0.01011675,0.0002537227,0.000658247,0.0001305811,0.000001688479,0.000004561236,0.00001922911,0.01715198,0.971045],"study_design_scores_gemma":[0.001948775,0.00007714325,8.812513e-7,0.004723725,0.001792259,0.00009549179,0.0000144743,0.000001007328,0.00009275073,0.00002016343,0.9910175,0.0002158381],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00002365184,0.9915342,0.000002337854,0.0001947801,0.0008205157,0.001126287,0.00007077078,0.00003068496,0.006196795],"genre_scores_gemma":[0.00001593913,0.9910632,0.0005991823,0.0001374012,0.000181319,0.0002428625,0.0002653917,0.00004177654,0.007452923],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9738655,"threshold_uncertainty_score":0.9999369,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02473578816740324,"score_gpt":0.3811810742160259,"score_spread":0.3564452860486226,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}