{"id":"W1744773367","doi":"10.1016/j.ajhg.2015.06.001","title":"Runs of Homozygosity: Association with Coronary Artery Disease and Gene Expression in Monocytes and Macrophages","year":2015,"lang":"en","type":"article","venue":"The American Journal of Human Genetics","topic":"Genetic Associations and Epidemiology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":47,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Ottawa","funders":"European Commission; National Institute for Health and Care Research; British Heart Foundation; Wellcome Trust; University of Leicester; NHS Blood and Transplant; American Heart Association","keywords":"Coronary artery disease; Internal medicine; Pathogenesis; Medicine; Cardiology; Disease; Case-control study; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001128069,0.0006566078,0.0006382415,0.001662536,0.001062644,0.001017352,0.0006095914,0.001258543,0.00430975],"category_scores_gemma":[0.003128878,0.0004036833,0.0008236074,0.001648019,0.0008925096,0.0003670178,0.000849452,0.001169811,0.0004162605],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001501157,"about_ca_system_score_gemma":0.0002442524,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001612872,"about_ca_topic_score_gemma":0.001453808,"domain_scores_codex":[0.9978587,0.001121196,0.0001853207,0.0003884474,0.0002307698,0.0002155282],"domain_scores_gemma":[0.995832,0.001828787,0.0009990055,0.000389164,0.000205283,0.0007458706],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.005246424,0.0002118734,0.9393601,0.00004911805,0.0008916369,0.003149795,0.0005558956,0.0002448506,0.04547124,0.0006040625,0.0003598779,0.003855098],"study_design_scores_gemma":[0.00007680615,0.0004268188,0.9923374,0.00001822049,0.0003929473,0.003216243,0.0003532791,0.0006744148,0.001248365,0.0009258098,0.0002910287,0.00003875242],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9985673,0.0002208659,0.0004543026,0.0001168874,0.00002172554,0.000003560017,0.000166089,0.00001344603,0.0004356698],"genre_scores_gemma":[0.9990128,0.00006717994,0.0003805643,0.000041161,0.0000502018,0.000006647548,0.0001035559,0.00001502862,0.000322711],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00430975,"threshold_uncertainty_score":0.01441753,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01386628857969076,"score_gpt":0.2617868313064524,"score_spread":0.2479205427267616,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}