{"id":"W1746592235","doi":"10.1371/journal.ppat.1005127","title":"Leptomonas seymouri: Adaptations to the Dixenous Life Cycle Analyzed by Genome Sequencing, Transcriptome Profiling and Co-infection with Leishmania donovani","year":2015,"lang":"en","type":"article","venue":"PLoS Pathogens","topic":"Research on Leishmaniasis Studies","field":"Medicine","cited_by":131,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Institute for Advanced Research","funders":"Central Drug Research Institute; Seventh Framework Programme; Université de Lausanne; Grantová Agentura České Republiky; London School of Hygiene and Tropical Medicine","keywords":"Biology; Leishmania donovani; Transcriptome; Parasite hosting; Vertebrate; Genome; Gene; Leishmania; Host (biology); Gene expression profiling; Genetics; Leishmaniasis; Visceral leishmaniasis; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006640152,0.0002087857,0.0002275935,0.0002915801,0.0002960689,0.0004099884,0.00009290695,0.0002069599,0.0006419579],"category_scores_gemma":[0.0001422214,0.0001078215,0.0002063912,0.0004784539,0.0001510056,0.0002215238,0.0003420989,0.0002994399,0.0001603456],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001512131,"about_ca_system_score_gemma":0.0001403568,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001123001,"about_ca_topic_score_gemma":0.001674353,"domain_scores_codex":[0.9999093,0.000008569073,0.000004912014,0.00003392268,0.00001782887,0.00002540803],"domain_scores_gemma":[0.9999352,0.00001212994,0.00002524649,0.000005197485,0.00001034916,0.00001187447],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001617415,0.00001510605,0.009397382,0.00008315517,0.000009940301,0.0001514476,0.0001465899,0.00005365851,0.9876524,0.00003456592,0.00004240262,0.002251582],"study_design_scores_gemma":[0.00002206765,0.0005434406,0.778015,0.00004767107,0.0001070635,0.001670781,0.002321209,0.001428423,0.2064215,0.0002523265,0.009128207,0.00004218641],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9976038,0.000516189,0.0005039984,0.0000502349,0.000006068256,0.00001086836,0.0008596794,0.00001596995,0.0004330753],"genre_scores_gemma":[0.9942999,0.0006834214,0.001269005,0.00006875631,0.000007801234,0.00003922102,0.002279361,0.00001175125,0.001340866],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001123001,"threshold_uncertainty_score":0.002232969,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05854459324574596,"score_gpt":0.2941010842380652,"score_spread":0.2355564909923193,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}