{"id":"W1746592235","doi":"10.1371/journal.ppat.1005127","title":"Leptomonas seymouri: Adaptations to the Dixenous Life Cycle Analyzed by Genome Sequencing, Transcriptome Profiling and Co-infection with Leishmania donovani","year":2015,"lang":"en","type":"article","venue":"PLoS Pathogens","topic":"Research on Leishmaniasis Studies","field":"Medicine","cited_by":131,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Institute for Advanced Research","funders":"Central Drug Research Institute; Seventh Framework Programme; Université de Lausanne; Grantová Agentura České Republiky; London School of Hygiene and Tropical Medicine","keywords":"Biology; Leishmania donovani; Transcriptome; Parasite hosting; Vertebrate; Genome; Gene; Leishmania; Host (biology); Gene expression profiling; Genetics; Leishmaniasis; Visceral leishmaniasis; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006241361,0.0002826946,0.0004580054,0.0002067219,0.0004141032,0.0001015695,0.0001294772,0.000080237,0.00002750926],"category_scores_gemma":[0.0004241262,0.0001912972,0.00007562378,0.0005897839,0.0001581755,0.0001803839,0.00005315524,0.0003387136,0.00008460857],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003231212,"about_ca_system_score_gemma":0.0003403289,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003352407,"about_ca_topic_score_gemma":0.000306811,"domain_scores_codex":[0.9976435,0.0001633262,0.0003439275,0.0005161222,0.0007756915,0.0005573825],"domain_scores_gemma":[0.9983151,0.00008203135,0.00009488655,0.0003753334,0.0005057793,0.0006268776],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0005676738,0.0004558456,0.0527356,0.0001714125,0.001048529,0.0001824762,0.01223463,0.0006306611,0.9294833,0.0001008232,0.001474164,0.0009148992],"study_design_scores_gemma":[0.02340388,0.01753316,0.7199455,0.00096629,0.004942895,0.001979117,0.04268944,0.02007921,0.1117887,0.0003289624,0.05225053,0.004092266],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9909767,0.00103813,0.001424671,0.002514205,0.00003931642,0.001568357,0.0001636925,0.0001821159,0.002092793],"genre_scores_gemma":[0.9960098,0.0002681959,0.002070141,0.0004963767,0.0002190953,0.00027086,0.00007877904,0.00006842845,0.0005183354],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8176945,"threshold_uncertainty_score":0.7800874,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05854459324574596,"score_gpt":0.2941010842380652,"score_spread":0.2355564909923193,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}