{"id":"W1747628444","doi":"10.1111/j.1462-5822.2012.01796.x","title":"Interferon‐gamma signals via an ERK1/2‐ARF6 pathway to promote bacterial internalization by gut epithelia","year":2012,"lang":"en","type":"article","venue":"Cellular Microbiology","topic":"Barrier Structure and Function Studies","field":"Neuroscience","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Canadian Institutes of Health Research","keywords":"Transcytosis; Internalization; Transcellular; Paracellular transport; Biology; Endocytosis; Cell biology; Barrier function; Epithelium; Tight junction; Interferon; Intestinal epithelium; Intestinal mucosa; MAPK/ERK pathway; Microbiology; Kinase; Cell; Immunology; Biochemistry; Permeability (electromagnetism); Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002144782,0.0002701274,0.000309783,0.0001027353,0.0001683337,0.00004648803,0.0003358086,0.0001858449,0.001003279],"category_scores_gemma":[0.00009608691,0.0002271769,0.00007526714,0.0001658028,0.0001476756,0.0002322528,0.0002092866,0.0001708663,0.0005809008],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004911939,"about_ca_system_score_gemma":0.0000164966,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001505506,"about_ca_topic_score_gemma":0.000006646735,"domain_scores_codex":[0.9982001,0.0003107469,0.0003535375,0.000526495,0.00005916819,0.000549918],"domain_scores_gemma":[0.9992287,0.00003890554,0.0001384321,0.0003384989,0.00005674063,0.0001987961],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001234596,0.00006249709,0.000234241,0.000008037519,0.00001492223,0.000003145544,0.001037161,8.535494e-7,0.9932663,0.0001644891,0.002313551,0.002771277],"study_design_scores_gemma":[0.0002102086,0.0002913112,0.0000460083,0.00000725185,0.00001118754,0.00005131786,0.00001958142,0.000006266736,0.7061116,0.0000645568,0.2929914,0.0001894035],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9445946,0.0002278708,0.05048576,0.0001287733,0.003643246,0.0003600858,0.0001545849,0.000106149,0.0002989386],"genre_scores_gemma":[0.9961163,0.00000973126,0.0001921494,0.001609443,0.0005895865,0.00002641335,0.0001227983,0.00003496213,0.001298585],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2906778,"threshold_uncertainty_score":0.9999099,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0189759625071624,"score_gpt":0.2370398515650317,"score_spread":0.2180638890578693,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}