{"id":"W1748906460","doi":"10.4049/jimmunol.180.10.6733","title":"The Ewing Sarcoma Protein (EWS) Binds Directly to the Proximal Elements of the Macrophage-Specific Promoter of the CSF-1 Receptor ( <i>csf1r</i> ) Gene","year":2008,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Arthritis and Musculoskeletal and Skin Diseases; RIKEN; Canada's Michael Smith Genome Sciences Centre","keywords":"Promoter; Chromatin immunoprecipitation; Molecular biology; Transcriptional regulation; Gene; Biology; Zinc finger; Binding site; Activator (genetics); Chromatin; Transfection; Cell biology; Gene expression; Transcription factor; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001961959,0.0004045137,0.0003427076,0.0002998015,0.0001707607,0.0002283771,0.0001346075,0.0002216128,0.001593899],"category_scores_gemma":[0.0002432922,0.0002120515,0.0003891558,0.0001648701,0.0003292202,0.0001937772,0.0003969606,0.0003875991,0.0006988841],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002956063,"about_ca_system_score_gemma":0.000245865,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004884672,"about_ca_topic_score_gemma":0.0005663729,"domain_scores_codex":[0.9998296,0.00001681051,0.00001184842,0.00006245916,0.00004379527,0.00003548307],"domain_scores_gemma":[0.9998723,0.0000314875,0.0000443271,0.00001159034,0.0000130945,0.00002718498],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002867214,0.00000726233,0.0004644867,0.00002817262,0.00000289908,0.00004262699,0.0000134144,0.00002416505,0.9982789,0.0001462788,0.00003550217,0.0009276729],"study_design_scores_gemma":[0.00001517364,0.0001751124,0.01830796,0.00001632112,0.00001401775,0.0005950832,0.00005467458,0.000592201,0.9735169,0.0002850123,0.006421266,0.00000629792],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9808601,0.002234058,0.01428983,0.0001368105,0.00003116303,0.0000439524,0.0006266216,0.000166324,0.001611007],"genre_scores_gemma":[0.9821292,0.001097883,0.0105805,0.000111256,0.00002529458,0.00003993885,0.00180738,0.00003121871,0.004177354],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001593899,"threshold_uncertainty_score":0.005332112,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01295155270936625,"score_gpt":0.2126427130850252,"score_spread":0.199691160375659,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}