{"id":"W1750901338","doi":"10.3390/biom5042808","title":"HIV-1 Recruits UPF1 but Excludes UPF2 to Promote Nucleocytoplasmic Export of the Genomic RNA","year":2015,"lang":"en","type":"article","venue":"Biomolecules","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":67,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Jewish General Hospital","funders":"Canadian Institutes of Health Research; Deutsche Forschungsgemeinschaft","keywords":"Nuclear export signal; Cell biology; RNA-binding protein; Biology; Ribonucleoprotein; Cajal body; Nuclear transport; RNA; Stress granule; Viral replication; Cytoplasm; Cell nucleus; RNA splicing; Molecular biology; Virology; Messenger RNA; Genetics; Gene; Virus","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001388528,0.0004317932,0.0002838538,0.0001967003,0.0003956864,0.0005483201,0.0002500253,0.0003462369,0.00236804],"category_scores_gemma":[0.0001948876,0.0002010563,0.0004253081,0.00009808312,0.0001554375,0.0003052773,0.0005717687,0.0004719871,0.0006727787],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003874322,"about_ca_system_score_gemma":0.0002179815,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001084225,"about_ca_topic_score_gemma":0.001324868,"domain_scores_codex":[0.9998536,0.00001221073,0.000005125147,0.00003536035,0.00004084002,0.00005273502],"domain_scores_gemma":[0.9999299,0.00001099554,0.00001356017,0.000008885891,0.00001113552,0.00002549114],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001983278,0.00003080716,0.0020337,0.00009682542,0.00001378628,0.000274538,0.0000361486,0.0002206288,0.9918382,0.0002668677,0.0002482897,0.004741875],"study_design_scores_gemma":[0.00004081821,0.0001468693,0.03035472,0.00002910782,0.00003445836,0.001378519,0.0001242415,0.005815452,0.9467486,0.0002375304,0.01506535,0.0000242899],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9922258,0.002793148,0.002412738,0.00008445035,0.00002715622,0.00001298925,0.0002582114,0.00008453529,0.002100893],"genre_scores_gemma":[0.9946542,0.0006063472,0.00186062,0.00006552797,0.00001048598,0.00001471018,0.000672026,0.00003099118,0.002085042],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00236804,"threshold_uncertainty_score":0.007921875,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03696910283391414,"score_gpt":0.2878883647055713,"score_spread":0.2509192618716572,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}