{"id":"W1750901338","doi":"10.3390/biom5042808","title":"HIV-1 Recruits UPF1 but Excludes UPF2 to Promote Nucleocytoplasmic Export of the Genomic RNA","year":2015,"lang":"en","type":"article","venue":"Biomolecules","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":67,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Jewish General Hospital","funders":"Canadian Institutes of Health Research; Deutsche Forschungsgemeinschaft","keywords":"Nuclear export signal; Cell biology; RNA-binding protein; Biology; Ribonucleoprotein; Cajal body; Nuclear transport; RNA; Stress granule; Viral replication; Cytoplasm; Cell nucleus; RNA splicing; Molecular biology; Virology; Messenger RNA; Genetics; Gene; Virus","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002644892,0.0001541998,0.0001554973,0.00005582138,0.0000662484,0.00002749143,0.0004903533,0.0001032447,0.000009004943],"category_scores_gemma":[0.0001909121,0.0001140482,0.000108649,0.0001498566,0.0001331136,0.000003828839,0.0003716188,0.00007196781,0.00005737394],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000315763,"about_ca_system_score_gemma":0.0002164851,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007406191,"about_ca_topic_score_gemma":0.00003792037,"domain_scores_codex":[0.9987941,0.00006855312,0.0002275167,0.0003223665,0.000254188,0.0003332332],"domain_scores_gemma":[0.9990013,0.00000522345,0.0000811423,0.000553626,0.0001330952,0.0002256265],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000093724,0.00003790262,0.001657895,0.00001469986,0.00002959203,0.000006361267,0.00006968618,0.00001415072,0.9901632,0.00005390981,0.005332568,0.002526325],"study_design_scores_gemma":[0.0003909536,0.0002670927,0.00371835,0.00003007357,0.000008324596,0.00002316829,0.0001476083,0.00004297292,0.9736605,0.00004295741,0.02151271,0.0001553075],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9964252,0.0004572898,0.0005397701,0.0005668079,0.0001206002,0.0003675301,0.00003766279,0.00001265012,0.001472543],"genre_scores_gemma":[0.9948428,0.00004030588,0.001225523,0.0002111231,0.0001261505,0.00002526392,0.00002200593,0.0000289032,0.003477883],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0165027,"threshold_uncertainty_score":0.465075,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03696910283391414,"score_gpt":0.2878883647055713,"score_spread":0.2509192618716572,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}