{"id":"W175253547","doi":"10.1007/s00204-002-0422-y","title":"Differential expression of c-fos and c-myc protooncogenes by estrogens, xenobiotics and other growth-stimulatory agents in primary rat hepatocytes","year":2003,"lang":"en","type":"article","venue":"Archives of Toxicology","topic":"Growth Hormone and Insulin-like Growth Factors","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Northern British Columbia","funders":"Flinders University","keywords":"Xenobiotic; Biology; Primary (astronomy); Differential (mechanical device); Chemistry; Gene expression; Endocrinology; Internal medicine; Cell biology; Biochemistry; Gene; Medicine; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000220234,0.000277618,0.0003301335,0.0004722351,0.0003288644,0.0003378642,0.0001601933,0.0001736668,0.001554978],"category_scores_gemma":[0.0001721741,0.0002430312,0.0004135542,0.0003353409,0.0003826832,0.0002728608,0.0002218896,0.0003963369,0.0003627494],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004073688,"about_ca_system_score_gemma":0.0003882628,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00238264,"about_ca_topic_score_gemma":0.004746918,"domain_scores_codex":[0.9997876,0.00003094351,0.00002023929,0.00003282092,0.00005567574,0.00007269344],"domain_scores_gemma":[0.9997634,0.00009499353,0.00001944962,0.00002549616,0.00004434722,0.00005237663],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006639988,0.00002974958,0.0004759547,0.00003233801,0.000006031883,0.00009899111,0.00004529167,0.00004184917,0.9975745,0.0001377686,0.00002958141,0.0008637927],"study_design_scores_gemma":[0.00001750637,0.0003357069,0.007071688,0.000003958868,0.00001696788,0.0001332646,0.0001095936,0.000193016,0.9911794,0.00004504374,0.0008892006,0.000004592069],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9939558,0.001653358,0.001518594,0.00006882973,0.0000439821,0.00001708225,0.000526164,0.00003718245,0.002179018],"genre_scores_gemma":[0.9896837,0.001345242,0.001395209,0.00005623269,0.00002744022,0.00004742842,0.001021764,0.00002013869,0.006402776],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00238264,"threshold_uncertainty_score":0.005201876,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01791123479220819,"score_gpt":0.2568599934396146,"score_spread":0.2389487586474064,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}