{"id":"W1758718687","doi":"10.1139/bcb-2014-0080","title":"Deception in simplicity: Hereditary phospholamban mutations in dilated cardiomyopathy","year":2014,"lang":"en","type":"review","venue":"Biochemistry and Cell Biology","topic":"Cardiac electrophysiology and arrhythmias","field":"Medicine","cited_by":50,"is_retracted":false,"has_abstract":true,"ca_institutions":"National Institute for Nanotechnology; University of Alberta","funders":"Canadian Institutes of Health Research; Alberta Innovates - Technology Futures; Heart and Stroke Foundation of Canada","keywords":"Phospholamban; SERCA; Contractility; Phosphorylation; Protein kinase A; Endoplasmic reticulum; Biology; Cell biology; Endocrinology; Internal medicine; Calcium; Homeostasis; Dilated cardiomyopathy; Mutant; Chemistry; Biochemistry; Heart failure; ATPase; Medicine; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001771016,0.0008718685,0.000596104,0.0005437756,0.0006524707,0.0004553263,0.0003747259,0.0009922539,0.002677187],"category_scores_gemma":[0.0007014631,0.0001362737,0.0003270267,0.0003272029,0.000873428,0.0005134658,0.0007836299,0.0008186346,0.0005186408],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00043343,"about_ca_system_score_gemma":0.0002190085,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008151939,"about_ca_topic_score_gemma":0.0009012995,"domain_scores_codex":[0.9997988,0.00002135404,0.00002260824,0.00006055682,0.00005217417,0.00004443575],"domain_scores_gemma":[0.9996978,0.0000548668,0.0001171465,0.00001069171,0.00001454266,0.0001049269],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"case_report","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0007049625,0.0002872424,0.05367412,0.000275135,0.000117989,0.798721,0.001463264,0.0005584121,0.101659,0.004013954,0.003545281,0.03497954],"study_design_scores_gemma":[0.00005848992,0.0006646179,0.1603632,0.0001214611,0.0001422171,0.8038263,0.0005231123,0.001459027,0.01365173,0.003052069,0.01606211,0.0000755268],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"review","genre_scores_codex":[0.9820114,0.00378883,0.002110306,0.002372656,0.0005361234,0.00004229104,0.0003318249,0.0001222713,0.008684197],"genre_scores_gemma":[0.9915313,0.001436185,0.001009283,0.0007758425,0.0003062799,0.000008270023,0.0001721182,0.00003636302,0.004724467],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.002677187,"threshold_uncertainty_score":0.008956015,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01068381016916772,"score_gpt":0.2780497446637165,"score_spread":0.2673659344945487,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}