{"id":"W1762931828","doi":"10.3390/proteomes3040328","title":"Mitochondrial Proteomics of Antimony and Miltefosine Resistant Leishmania infantum","year":2015,"lang":"en","type":"article","venue":"Proteomes","topic":"Research on Leishmaniasis Studies","field":"Medicine","cited_by":33,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"Canadian Institutes of Health Research","keywords":"Biology; Leishmania; Miltefosine; Mitochondrion; Leishmania donovani; Mutant; Proteome; Isocitrate dehydrogenase; Proteomics; Cell biology; Leishmania mexicana; Biochemistry; Leishmaniasis; Parasite hosting; Genetics; Visceral leishmaniasis; Enzyme; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004139565,0.0001996848,0.0005661775,0.0001939252,0.00006933446,0.00003179246,0.0001300771,0.00009511189,0.00003490865],"category_scores_gemma":[0.001383909,0.0001548707,0.00006915491,0.0002496977,0.0003523323,0.0001380538,0.0002206556,0.0002325714,0.0000239459],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000688182,"about_ca_system_score_gemma":0.000264383,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001716322,"about_ca_topic_score_gemma":0.00001506014,"domain_scores_codex":[0.9981838,0.00007377212,0.000408491,0.0003388014,0.0006332787,0.0003618647],"domain_scores_gemma":[0.9986517,0.00005235927,0.000143869,0.0003947791,0.0004832651,0.0002740422],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.006891763,0.0007008588,0.1579864,0.001941943,0.0006283554,0.0002578114,0.003219922,0.000003130362,0.7905495,0.001666214,0.03165921,0.004494912],"study_design_scores_gemma":[0.01845928,0.007211461,0.273712,0.001210287,0.0003210735,0.0002222014,0.001819946,0.0004421153,0.6548648,0.004616033,0.03618638,0.0009343416],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9881331,0.001818244,0.0001174882,0.003362376,0.0001243128,0.002468192,0.00001900795,0.00006965527,0.003887675],"genre_scores_gemma":[0.9696282,0.0003310938,0.02784287,0.00008778698,0.0003889569,0.0002675083,0.000009305501,0.00004843484,0.001395867],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1356847,"threshold_uncertainty_score":0.6315444,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04144067871054476,"score_gpt":0.3047695016495663,"score_spread":0.2633288229390216,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}