{"id":"W1764553207","doi":"10.1186/s13072-015-0035-3","title":"Characterization of whole-genome autosomal differences of DNA methylation between men and women","year":2015,"lang":"en","type":"article","venue":"Epigenetics & Chromatin","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":260,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Münchner Zentrum für Gesundheitswissenschaften; Seventh Framework Programme; Wellcome Trust; Biotechnology and Biological Sciences Research Council; Human Genetics Foundation-Torino; Medical Research Council; Directorate for Biological Sciences; United States - Israel Binational Science Foundation; Helmholtz Zentrum München; Bundesministerium für Bildung und Forschung; Panel on Research Ethics; Israel Science Foundation; Bundesministerium für Gesundheit; Business Events Perth; United States-Israel Binational Science Foundation; University of Bristol; Tel Aviv University; European Commission; Compagnia di San Paolo; Associazione Italiana per la Ricerca sul Cancro; National Science Foundation; Oak Foundation; Wellcome; Department of Science and Technology, Ministry of Science and Technology, India; German-Israeli Foundation for Scientific Research and Development","keywords":"Biology; DNA methylation; Epigenome; CpG site; Epigenetics; Genetics; Autosome; Human genetics; Gene; Evolutionary biology; X chromosome; Gene expression","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003467847,0.0001499386,0.0001649842,0.0004769819,0.0001464971,0.0002301927,0.0001688995,0.0001693171,0.004314891],"category_scores_gemma":[0.0007380712,0.00009134824,0.0002221428,0.0004731484,0.0001566343,0.0001088345,0.000213941,0.0001582185,0.0002529412],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001162286,"about_ca_system_score_gemma":0.0001173248,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009698864,"about_ca_topic_score_gemma":0.001375641,"domain_scores_codex":[0.9998268,0.00003148615,0.00001417336,0.00008502105,0.00002053468,0.00002204711],"domain_scores_gemma":[0.9997119,0.00009721638,0.00009126235,0.00003829786,0.00002696555,0.00003426332],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.000517445,0.00002067823,0.9293733,0.00007767469,0.0004120035,0.0001190844,0.0002168189,0.000105234,0.05489471,0.0002618535,0.0001879621,0.01381322],"study_design_scores_gemma":[0.000006183993,0.00007332788,0.9940679,0.000007411103,0.00007031103,0.0003988488,0.00006872664,0.0001254462,0.004271331,0.0001843997,0.0007232238,0.000002838332],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9947514,0.0013151,0.00122258,0.00004789063,0.000007500742,0.000008766296,0.001614681,0.0000146083,0.001017528],"genre_scores_gemma":[0.9983426,0.0002458041,0.0004591269,0.00002622866,0.000005619375,0.000008786649,0.0005361305,0.000005589818,0.000369985],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004314891,"threshold_uncertainty_score":0.01443475,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02100399541637379,"score_gpt":0.2511278178894839,"score_spread":0.2301238224731101,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}