{"id":"W1764553207","doi":"10.1186/s13072-015-0035-3","title":"Characterization of whole-genome autosomal differences of DNA methylation between men and women","year":2015,"lang":"en","type":"article","venue":"Epigenetics & Chromatin","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":260,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Münchner Zentrum für Gesundheitswissenschaften; Seventh Framework Programme; Wellcome Trust; Biotechnology and Biological Sciences Research Council; Human Genetics Foundation-Torino; Medical Research Council; Directorate for Biological Sciences; United States - Israel Binational Science Foundation; Helmholtz Zentrum München; Bundesministerium für Bildung und Forschung; Panel on Research Ethics; Israel Science Foundation; Bundesministerium für Gesundheit; Business Events Perth; United States-Israel Binational Science Foundation; University of Bristol; Tel Aviv University; European Commission; Compagnia di San Paolo; Associazione Italiana per la Ricerca sul Cancro; National Science Foundation; Oak Foundation; Wellcome; Department of Science and Technology, Ministry of Science and Technology, India; German-Israeli Foundation for Scientific Research and Development","keywords":"Biology; DNA methylation; Epigenome; CpG site; Epigenetics; Genetics; Autosome; Human genetics; Gene; Evolutionary biology; X chromosome; Gene expression","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004185559,0.0001594043,0.0002947096,0.00008307243,0.00003479064,0.00001563768,0.0001411136,0.0001636813,0.000008300267],"category_scores_gemma":[0.0001074315,0.000157723,0.00003948667,0.000124671,0.0001121491,0.000007187727,0.0001061432,0.00004628644,0.000001966045],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001856743,"about_ca_system_score_gemma":0.00008707277,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001253924,"about_ca_topic_score_gemma":0.000002681968,"domain_scores_codex":[0.9986927,0.0001306089,0.0004924283,0.0002559224,0.0002365344,0.0001918066],"domain_scores_gemma":[0.9990215,0.00002498564,0.0003755152,0.0002658599,0.0001803276,0.0001317841],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001766259,0.00003455744,0.03673702,0.00004492872,0.00004481065,1.330413e-7,0.0009280942,0.00002521401,0.9586635,0.00002178523,0.000002475493,0.003479773],"study_design_scores_gemma":[0.0003600441,0.0004618883,0.3730108,0.00001104103,0.00001963015,2.410926e-7,0.0001326355,0.0001052825,0.6248551,0.0003193932,0.0006032651,0.0001207329],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9941083,0.0006551856,0.00427214,0.00004018125,0.00005143818,0.0002145385,0.0001353759,0.000008173552,0.0005146438],"genre_scores_gemma":[0.9973912,0.0002199958,0.001522479,0.00000627683,0.0001434507,0.00001529996,0.000516894,0.00002174326,0.0001626207],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3362737,"threshold_uncertainty_score":0.6431757,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02100399541637379,"score_gpt":0.2511278178894839,"score_spread":0.2301238224731101,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}