{"id":"W176944265","doi":"10.1177/135965350100600206","title":"Avanti 3: A Randomized, Double-Blind Trial to Compare the Efficacy and Safety of Lamivudine plus Zidovudine versus Lamivudine plus Zidovudine plus Nelfinavir in HIV-1-Infected Antiretroviral-Naive Patients","year":2001,"lang":"en","type":"article","venue":"Antiviral Therapy","topic":"HIV/AIDS drug development and treatment","field":"Medicine","cited_by":43,"is_retracted":false,"has_abstract":true,"ca_institutions":"Sunnybrook Health Science Centre; St. Paul's Hospital","funders":"","keywords":"Lamivudine; Nelfinavir; Zidovudine; Medicine; Tolerability; Placebo; Gastroenterology; Internal medicine; Adverse effect; Pharmacology; Randomized controlled trial; Indinavir; Virology; Sida; Viral load; Human immunodeficiency virus (HIV); Viral disease; Antiretroviral therapy; Virus","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001070355,0.000846529,0.002624198,0.000624424,0.0002680944,0.00006923658,0.0003520809,0.0001874867,0.0001604618],"category_scores_gemma":[0.000374627,0.0005584625,0.0004049591,0.001568644,0.0004510439,0.0002689743,0.0002094548,0.0004997033,0.00009731507],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004629776,"about_ca_system_score_gemma":0.0003961962,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003139797,"about_ca_topic_score_gemma":0.0001223213,"domain_scores_codex":[0.9953902,0.0004126145,0.001493791,0.0008986223,0.0008547531,0.0009499534],"domain_scores_gemma":[0.9971493,0.001007672,0.0005072646,0.0007171005,0.0003227504,0.0002959395],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.926188,0.00125174,0.06245791,0.00004008229,0.0009174234,0.0001315231,0.002089006,0.00006307282,0.000291459,0.0002729732,0.001362162,0.004934684],"study_design_scores_gemma":[0.9569485,0.002498111,0.03221243,0.0003701645,0.0003395366,0.00001357007,0.0001707661,0.0006427101,0.001162026,0.00002097401,0.005037792,0.0005834281],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9837945,0.0007409641,0.0001413493,0.003511677,0.0006985451,0.008483175,0.00005748652,0.0001265797,0.00244579],"genre_scores_gemma":[0.9913285,0.003467734,0.0003293212,0.0002527198,0.0003636444,0.0002565593,0.0005580632,0.00009432205,0.003349125],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03076053,"threshold_uncertainty_score":0.9996867,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04664450726182794,"score_gpt":0.318903719057104,"score_spread":0.2722592117952761,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}