{"id":"W1769581193","doi":"10.1016/bs.pmbts.2015.06.005","title":"A2E and Lipofuscin","year":2015,"lang":"en","type":"review","venue":"Progress in molecular biology and translational science","topic":"Retinal Diseases and Treatments","field":"Medicine","cited_by":51,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"National Center for Research Resources; National Institute of General Medical Sciences; National Eye Institute; National Institutes of Health; AGE-WELL","keywords":"Lipofuscin; Retinal pigment epithelium; Macular degeneration; Retinal; Chemistry; Retina; Anatomy; Biology; Cell biology; Pathology; Biochemistry; Ophthalmology; Neuroscience; Medicine","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004602984,0.0009931078,0.001116384,0.001704236,0.0002486975,0.0008595068,0.0005786722,0.001094204,0.003340047],"category_scores_gemma":[0.0006250035,0.0002676795,0.0003344488,0.001360701,0.0005336595,0.001301508,0.0007723958,0.001849294,0.001662839],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004413714,"about_ca_system_score_gemma":0.000957537,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008875554,"about_ca_topic_score_gemma":0.001841216,"domain_scores_codex":[0.9998885,0.0000152322,0.00002086339,0.00002061396,0.00004194641,0.00001282042],"domain_scores_gemma":[0.9998096,0.00008397484,0.00003455766,0.000006976676,0.00004152931,0.00002351431],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001396342,0.00007295488,0.0001503712,0.01155241,0.00009102694,0.0003188822,0.00003465758,0.0002742986,0.002615047,0.003327045,0.03260471,0.948819],"study_design_scores_gemma":[0.00004464928,0.00007350289,0.0005624783,0.002439362,0.0001446462,0.001463797,0.0000448953,0.00009134165,0.0008175271,0.003197808,0.9910989,0.00002098831],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00008414313,0.9985178,0.0001167971,0.0002505117,0.0002343157,0.0000029537,0.0000111156,0.000005985097,0.0007763821],"genre_scores_gemma":[0.0007889141,0.9976292,0.0002177763,0.000260617,0.000288082,0.000005607728,0.00002475398,0.000001353199,0.000783683],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003340047,"threshold_uncertainty_score":0.01117355,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03848158967390738,"score_gpt":0.4389911921574032,"score_spread":0.4005096024834959,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}